ArticleClinical interventions in aging2018
Costs of medication in older patients: before and after comprehensive geriatric assessment.
Article in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Prevalence of Polypharmacy and Potentially Inappropriate Medications Use in Elderly Chinese Patients: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2022Pooled it
- Indirect comparison of efficacy between different antibiotic prophylaxis against the intracranial infection after craniotomy.Antimicrobial resistance and infection control · 2020Pooled it
- Validity of the Turkish version of the Oral Frailty Index-8 and its relationship with frailty, malnutrition, and sarcopenia in older adults.Turkish journal of medical sciences · 2026Article
- Reducing Anticholinergic Burden in Hospitalised Older Adults: Analysis From the INFAR Study.Basic & clinical pharmacology & toxicology · 2026Article
- Screening criteria of potentially inappropriate medications and associations of exposure timing with incident hospital admissions among older adults in a rural community hospital.BMC geriatrics · 2025Article
- The Relationship Between FIB-4 Score and Dynapenia in Older Adults.Diagnostics (Basel, Switzerland) · 2025Article
- An Instant Relationship Between Hyponatremia, Geriatric Syndromes, and Drugs in Older Adults: A Cross-Sectional Analysis from a Single Geriatric Clinic.Diagnostics (Basel, Switzerland) · 2025Article
- Osteoporosis in older patients with idiopathic normal pressure hydrocephalus.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Antiseizure Medication Withdrawal, Risk of Epilepsy, and Longterm EEG Trends in Acute Symptomatic Seizures or Epileptic EEG Patterns.Neurology. Clinical practice · 2024Article
- Sarcopenia in older patients with idiopathic normal pressure hydrocephalus: an observational study from a single geriatric clinic in Turkey.Acta neurologica Belgica · 2024Observational
- Association between Cognitive Impairment Severity and Polypharmacy in Older Patients with Atrial Fibrillation: A Retrospective Study Using Inpatient Data from a Specialised Geriatric Hospital.Geriatrics (Basel, Switzerland) · 2024Article
- Enhancing medication management of older adults in Qatar: healthcare professionals' perspectives on challenges, barriers and enabling solutions.Therapeutic advances in drug safety · 2024Article
- Sarcopenia, but not malnutrition, is associated with fear of falling in older patients with dementia.Northern clinics of Istanbul · 2024Article
- Potentially inappropriate medicine use and predicting risk factors in hospitalized older adult patients: findings of a prospective observational study from Ethiopia.Journal of pharmaceutical policy and practice · 2023Article
- Predictive Strategies to Reduce the Risk of Rehospitalization with a Focus on Frail Older Adults: A Narrative Review.Epidemiologia (Basel, Switzerland) · 2023Review
- Analysis of the incidence of falls and related factors in elderly patients based on comprehensive geriatric assessment.Aging medicine (Milton (N.S.W)) · 2023Article
- Assessment of Drug-Related Problems and Health-Related Quality of Life Domains in Elderly Patients with Type 2 Diabetes Mellitus.Therapeutics and clinical risk management · 2023Article
- Cost-Related Medication Nonadherence and Patient Cost Responsibility for Rural and Urban Cancer Survivors.JCO oncology practice · 2022Article
- Association between comprehensive geriatric assessment and polypharmacy at discharge in patients with ischaemic stroke: A nationwide, retrospective, cohort study.EClinicalMedicine · 2022Article
- Sociodemographic and Health-Related Factors Influencing Drug Intake among the Elderly Population.International journal of environmental research and public health · 2022Article
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4 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPolypharmacy and inappropriate drug use cause numerous complications, such as cognitive impairment, frailty, falls, and functional dependence. The present study aimed to determine the effect of the comprehensive geriatric assessment (CGA) on polypharmacy, potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), and to evaluate the economic reflections of medication changes.
methodsOne thousand five hundred and seventy-nine older patients, who had undergone CGA, were retrospectively evaluated. The drugs, drug groups, and number of drugs that the patients used were recorded. Appropriate drug therapy was identified by both CGA and STOPP/START criteria. Based on these criteria, PIMs were discontinued and PPOs were started. The monthly cost of these drugs was calculated separately for PIMs and PPOs by using the drugstore records.
resultsAfter CGA, while the prevalence of non-polypharmacy was increased from 43.3% to 65.6%, the prevalence of polypharmacy and hyperpolypharmacy was decreased from 56.7% to 34.4% and 12.0% to 3.6%, respectively. The three most common PIMs discontinued were proton pump inhibitors, anti-dementia drugs, and antipsychotics, respectively. However, the most common PPOs started were vitamin D and B12 supplements, and anti-depressants. After CGA, monthly saved total per capita cost of PIMs was US$12.8 and monthly increased total per capita cost of PPOs was $5.6.
conclusionIt was demonstrated that prevalence of polypharmacy, PIM, and PPO could be decreased by CGA including START/STOPP criteria in older adults. Furthermore, this will have beneficial effects on economical parameters due to decreasing drug-related health care costs.
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