Evidence map›Paper›PMID 29674730›Full record

ArticleScientific reports2018

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts.

Aline Jelenkovic, Reijo Sund, Yoshie Yokoyama, Yoon-Mi Hur, Vilhelmina Ullemar, Catarina Almqvist, Patrik Ke Magnusson, Gonneke Willemsen, Meike Bartels, Catharina Em van Beijsterveldt and 48 more

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019
    Trial
  2. Article
  3. Genetic and Environmental Contributions to Child Height in Low- and Middle-Income Countries.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

58 authors.

Aline JelenkovicDepartment of Social Research, University of Helsinki, Helsinki, Finland. aline.jelenkovic@helsinki.fi.
Reijo SundDepartment of Social Research, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6268-8117
Yoshie YokoyamaDepartment of Public Health Nursing, Osaka City University, Osaka, Japan.
Yoon-Mi HurDepartment of Education, Mokpo National University, Jeonnam, South Korea.
Vilhelmina UllemarDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Catarina AlmqvistDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Patrik Ke MagnussonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-7315-7899
Gonneke WillemsenDepartment of Biological Psychology, VU University Amsterdam, Amsterdam, Netherlands.
Meike BartelsDepartment of Biological Psychology, VU University Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-9667-7555
Catharina Em van BeijsterveldtDepartment of Biological Psychology, VU University Amsterdam, Amsterdam, Netherlands.
Leonie H BoglInstitute for Molecular Medicine FIMM, Helsinki, Finland.
Kirsi H PietiläinenObesity Research Unit, Research Programs Unit, University of Helsinki, Helsinki, Finland.
Eero VuoksimaaInstitute for Molecular Medicine FIMM, Helsinki, Finland.
Fuling JiDepartment of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, China.
Feng NingDepartment of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, China.
Zengchang PangDepartment of Noncommunicable Diseases Prevention, Qingdao Centers for Disease Control and Prevention, Qingdao, China.
Tracy L NelsonDepartment of Health and Exercise Sciencies and Colorado School of Public Health, Colorado State University, Fort Collins, USA.
Keith E WhitfieldPsychology and Neuroscience, Duke University, Durham, NC, USA.
Esther RebatoDepartment of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, Leioa, Spain.
Clare H LlewellynHealth Behaviour Research Centre, Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London, UK.ORCID 0000-0002-0066-2827
Abigail FisherHealth Behaviour Research Centre, Department of Epidemiology and Public Health, Institute of Epidemiology and Health Care, University College London, London, UK.
Gombojav BayasgalanHealthy Twin Association of Mongolia, Ulaanbaatar, Mongolia.
Danshiitsoodol NarandalaiHealthy Twin Association of Mongolia, Ulaanbaatar, Mongolia.
Morten Bjerregaard-AndersenBandim Health Project, INDEPTH Network, Bissau, Guinea-Bissau.
Henning Beck-NielsenDepartment of Endocrinology, Odense University Hospital, Odense, Denmark.
Morten SodemannDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Adam D TarnokiDepartment of Radiology, Semmelweis University, Budapest, Hungary.
David L TarnokiDepartment of Radiology, Semmelweis University, Budapest, Hungary.
Syuichi OokiDepartment of Health Science, Ishikawa Prefectural Nursing University, Kahoku, Ishikawa, Japan.
Maria A StaziIstituto Superiore di Sanità - Centre for Behavioural Sciences and Mental Health, Rome, Italy.
Corrado FagnaniIstituto Superiore di Sanità - Centre for Behavioural Sciences and Mental Health, Rome, Italy.
Sonia BrescianiniIstituto Superiore di Sanità - Centre for Behavioural Sciences and Mental Health, Rome, Italy.
Lise DuboisSchool of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Michel BoivinÉcole de psychologie, Université Laval, Québec, Canada.
Mara BrendgenDépartement de psychologie, Université du Québec à Montréal, Montréal, Québec, Canada.
Ginette DionneÉcole de psychologie, Université Laval, Québec, Canada.
Frank VitaroÉcole de psychoéducation, Université de Montréal, Montréal, Québec, Canada.
Tessa L CutlerThe Australian Twin Registry, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Victoria, Australia.
John L HopperThe Australian Twin Registry, Centre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Victoria, Australia.
Robert F KruegerDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-9127-5509
Matt McGueDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
Shandell PahlenDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.
Jeffrey M CraigMurdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.ORCID 0000-0003-3979-7849
Richard SafferyMurdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.ORCID 0000-0002-9510-4181
Claire Ma HaworthMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Robert PlominKing's College London, MRC Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Ariel Knafo-NoamThe Hebrew University of Jerusalem, Jerusalem, Israel.
David MankutaHadassah Hospital Obstetrics and Gynecology Department, Hebrew University Medical School, Jerusalem, Israel.
Lior AbramsonThe Hebrew University of Jerusalem, Jerusalem, Israel.
S Alexandra BurtMichigan State University, East Lansing, Michigan, USA.
Kelly L KlumpMichigan State University, East Lansing, Michigan, USA.
Robert F VlietinckCentre of Human Genetics, University Hospitals Leuven, Leuven, Belgium.
Catherine A DeromCentre of Human Genetics, University Hospitals Leuven, Leuven, Belgium.
Ruth Jf LoosThe Charles Bronfman Institute for Personalized Medicine, The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-8532-5087
Dorret I BoomsmaDepartment of Biological Psychology, VU University Amsterdam, Amsterdam, Netherlands.
Thorkild I A SørensenNovo Nordisk Foundation Centre for Basic Metabolic Research (Section of Metabolic Genetics), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jaakko KaprioInstitute for Molecular Medicine FIMM, Helsinki, Finland.ORCID 0000-0002-3716-2455
Karri SilventoinenDepartment of Social Research, University of Helsinki, Helsinki, Finland.

Funding

The Effects of Estradiol on Genetic Risk for Disordered Eating During PubertyR01MH092377 · NIMH · MICHIGAN STATE UNIVERSITY · PI KLUMP, KELLY L · 2010 to 2014
$3.4M
Integrating contextual, proximal, and individual risks for child conduct problemsR01HD066040 · NICHD · MICHIGAN STATE UNIVERSITY · PI BURT, S. ALEXANDRA · 2010 to 2014
$2.9M
Gene-environment Interactions in Childhood Conduct ProblemsR01MH081813 · NIMH · MICHIGAN STATE UNIVERSITY · PI BURT, S. ALEXANDRA · 2008 to 2013
$1.6M
Hormones in Sex-different Developmental PsychopathologyR21MH070542 · NIMH · MICHIGAN STATE UNIVERSITY · PI NIGG, JOEL T · 2005 to 2007
$475k
Biotechnology and Biological Sciences Research Council 31/D19086Canadian Institutes for Health ResearchCancer Research UK C1418/A7974European Research Council 230374Medical Research Council G0500079Medical Research Council G0901245Medical Research Council G19/2Medical Research Council MR/M021475/1NICHD NIH HHS R01 HD066040NIMH NIH HHS R01 MH081813NIMH NIH HHS R01 MH092377NIMH NIH HHS R21 MH070542
6 · The paper itself

Abstract

It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 twin cohorts in 15 countries derived from the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins), including 67,850 dizygotic twin individuals. Linear regression analyses showed that boys having a co-twin sister were, on average, 31 g (95% CI 18 to 45) heavier and 0.16 cm (95% CI 0.045 to 0.274) longer than those with a co-twin brother. In girls, birth size was not associated (5 g birth weight; 95% CI -8 to -18 and -0.089 cm birth length; 95% CI -0.202 to 0.025) with the sex of the co-twin. Gestational age was slightly shorter in boy-boy pairs than in boy-girl and girl-girl pairs. When birth size was standardized by gestational age, the magnitude of the associations was attenuated in boys, particularly for birth weight. In conclusion, boys with a co-twin sister are heavier and longer at birth than those with a co-twin brother. However, these differences are modest and partly explained by a longer gestation in the presence of a co-twin sister.

Indexed as

Birth WeightBody HeightGestational AgeTwins, DizygoticCohort StudiesFemaleHumansMale

Identifiers

PMID29674730
PMCPMC5908858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.