Evidence map›Paper›PMID 29674431›Full record

ArticleScience (New York, N.Y.)2018

Cell type transcriptome atlas for the planarian

Christopher T Fincher, Omri Wurtzel, Thom de Hoog, Kellie M Kravarik, Peter W Reddien

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 255 papers.

0numbers the graph read from it
0cells of the map it votes in
255citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

255 citing papers in PubMed.

  1. Article
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  15. eLife · 2026
    Article
  16. Article
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  19. Decoding cnidarian cell type gene regulation.Nature ecology & evolution · 2026
    Article
  20. Article

195 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher T FincherWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.ORCID 0000-0003-0022-1260
Omri WurtzelWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Thom de HoogWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Kellie M KravarikWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
Peter W ReddienWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. reddien@wi.mit.edu.ORCID 0000-0002-5569-333X

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Stem cell and regeneration regulatory genes in planariansR01GM080639 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI REDDIEN, PETER · 2008 to 2020
$4.6M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM080639NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

The transcriptome of a cell dictates its unique cell type biology. We used single-cell RNA sequencing to determine the transcriptomes for essentially every cell type of a complete animal: the regenerative planarian

Indexed as

Atlases as TopicTranscriptomeAnimalsCell LineageCellsGene Expression ProfilingPlanariansSequence Analysis, RNASingle-Cell AnalysisStem Cells

Identifiers

PMID29674431
PMCPMC6563842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.