Evidence map›Paper›PMID 29674411›Full record

ArticleAJNR. American journal of neuroradiology2018

Sequential Apparent Diffusion Coefficient for Assessment of Tumor Progression in Patients with Low-Grade Glioma.

I E Chen, N Swinburne, N M Tsankova, M M Hefti, A Aggarwal, A H Doshi, A Hormigo, B N Delman, K Nael

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

I E ChenFrom the Departments of Radiology (I.E.C., N.S., A.A., A.H.D., B.N.D., K.N.).ORCID 0000-0003-1394-6543
N SwinburneFrom the Departments of Radiology (I.E.C., N.S., A.A., A.H.D., B.N.D., K.N.).ORCID 0000-0001-5831-7287
N M TsankovaPathology (N.M.T., M.M.H.).ORCID 0000-0002-5333-312X
M M HeftiPathology (N.M.T., M.M.H.).ORCID 0000-0002-3127-4528
A AggarwalFrom the Departments of Radiology (I.E.C., N.S., A.A., A.H.D., B.N.D., K.N.).ORCID 0000-0002-9562-6457
A H DoshiFrom the Departments of Radiology (I.E.C., N.S., A.A., A.H.D., B.N.D., K.N.).ORCID 0000-0002-2507-436X
A HormigoNeurology (A.H.), Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0003-3259-5603
B N DelmanFrom the Departments of Radiology (I.E.C., N.S., A.A., A.H.D., B.N.D., K.N.).ORCID 0000-0002-9792-8942
K NaelFrom the Departments of Radiology (I.E.C., N.S., A.A., A.H.D., B.N.D., K.N.) Kambiznael@gmail.com.ORCID 0000-0002-4194-9488

Funding

Resolving SARS-Cov-2 tropism and COVID19 pathology in the brainR01NS106229 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Nadejda Mincheva Tsankova · 2019 to 2026
$3.5M
NINDS NIH HHS R01 NS106229
6 · The paper itself

Abstract

background and purposeEarly and accurate identification of tumor progression in patients with low-grade gliomas is challenging. We aimed to assess the role of quantitative ADC analysis in the sequential follow-up of patients with low-grade gliomas as a potential imaging marker of tumor stability or progression. MATERIALS AND

methodsIn this retrospective study, patients with a diagnosis of low-grade glioma with at least 12 months of imaging follow-up were retrospectively reviewed. Two neuroradiologists independently reviewed sequential MR imaging in each patient to determine tumor progression using the Response Assessment in Neuro-Oncology criteria. Normalized mean ADC (ADC

resultsTwenty-eight of 69 patients who were evaluated met our inclusion criteria. Fifteen patients were classified as stable versus 13 patients as having progression based on consensus reads of MRIs and the Response Assessment in Neuro-Oncology criteria. The interval change of ADC values showed greater concordance with ultimate lesion disposition than quantitative ADC values at a single time point. The interval change in ADC

conclusionsThe interval change of ADC

Indexed as

AdultAgedBrain NeoplasmsDiffusion Magnetic Resonance ImagingDisease ProgressionFemaleGliomaHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID29674411
PMCPMC7410604

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.