Evidence map›Paper›PMID 29674365›Full record

ArticleBMJ open2018

Protocol of a Multicenter International Randomized Controlled Manikin Study on Different Protocols of Cardiopulmonary Resuscitation for laypeople (MANI-CPR).

Enrico Baldi, Enrico Contri, Roman Burkart, Paola Borrelli, Ottavia Eleonora Ferraro, Michela Tonani, Amedeo Cutuli, Daniele Bertaia, Pasquale Iozzo, Caroline Tinguely and 11 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02632500 (Multicenter internAtional raNdomized Controlled manIkin Study on Different Protocols of CPR), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02632500 nacompletednot on this map

Multicenter internAtional raNdomized Controlled manIkin Study on Different Protocols of CPR (MANI-CPR)

TypeinterventionalSponsorPavia nel CuoreRan2016 to 2019Enrolled576ConditionsQuality of Cardio-pulmonary ResuscitationArmsQuality of chest compressions
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Enrico BaldiPavia nel Cuore ONLUS, Pavia, Italy.ORCID 0000-0002-6360-224X
Enrico ContriPavia nel Cuore ONLUS, Pavia, Italy.
Roman BurkartSwiss Resuscitation Council, Bern, Switzerland.
Paola BorrelliUnit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Ottavia Eleonora FerraroUnit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Michela TonaniPavia nel Cuore ONLUS, Pavia, Italy.
Amedeo CutuliPavia nel Cuore ONLUS, Pavia, Italy.
Daniele BertaiaRobbio nel Cuore ONLUS, Robbio, Italy.
Pasquale IozzoGeneral Intensive Care Unit, Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy.
Caroline TinguelyEmergency Training Center, Cugy, Switzerland.
Daniel LopezEmergency Training Center, Cugy, Switzerland.
Susi BoldarinCentro Studi e Formazione Gymnasium, Pordenone, Italy.
Claudio DeiuriCentro Studi e Formazione Gymnasium, Pordenone, Italy.
Sandrine DénéréazÉcole Supérieure d'Ambulancier et Soins d'Urgence Romande (ES-ASUR), Lausanne, Switzerland.
Yves DénéréazÉcole Supérieure d'Ambulancier et Soins d'Urgence Romande (ES-ASUR), Lausanne, Switzerland.
Michael TerraponFormaMed Sàrl, Cortaillod, Switzerland.
Christian TamiFederazione Cantonale Ticinese Servizi Autoambulanze, Lugano, Switzerland.
Cinzia CeredaFederazione Cantonale Ticinese Servizi Autoambulanze, Lugano, Switzerland.
Alberto SomaschiniPavia nel Cuore ONLUS, Pavia, Italy.
Stefano CornaraPavia nel Cuore ONLUS, Pavia, Italy.
Andrea CortegianiSection of Anesthesia Analgesia, Intensive Care and Emergency, Department of Biopathology and Medical Biotechnologies (DIBIMED), Policlinico Paolo Giaccone, University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOut-of-hospital cardiac arrest is one of the leading causes of death in industrialised countries. Survival depends on prompt identification of cardiac arrest and on the quality and timing of cardiopulmonary resuscitation (CPR) and defibrillation. For laypeople, there has been a growing interest on hands-only CPR, meaning continuous chest compression without interruption to perform ventilations. It has been demonstrated that intentional interruptions in hands-only CPR can increase its quality. The aim of this randomised trial is to compare three CPR protocols performed with different intentional interruptions with hands-only CPR. METHODS AND ANALYSIS: This is a prospective randomised trial performed in eight training centres. Laypeople who passed a basic life support course will be randomised to one of the four CPR protocols in an 8 min simulated cardiac arrest scenario on a manikin: (1) 30 compressions and 2 s pause; (2) 50 compressions and 5 s pause; (3) 100 compressions and 10 s pause; (4) hands-only. The calculated sample size is 552 people. The primary outcome is the percentage of chest compression performed with correct depth evaluated by a computerised feedback system (Laerdal QCPR). ETHICS AND DISSEMINATION: . Due to the nature of the study, we obtained a waiver from the Ethics Committee (IRCCS Policlinico San Matteo, Pavia, Italy). All participants will sign an informed consent form before randomisation. The results of this study will be published in peer-reviewed journal. The data collected will also be made available in a public data repository. TRIAL REGISTRATION NUMBER: NCT02632500.

Indexed as

Cardiopulmonary ResuscitationManikinsOut-of-Hospital Cardiac ArrestHumansItalyProspective StudiesRandomized Controlled Trials as Topiccardiopulmonary resuscitationfeedback devicestraining

Identifiers

PMID29674365
PMCPMC5914707

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.