ArticleBMJ open2018
Health and Prevention Enhancement (H-PEACE): a retrospective, population-based cohort study conducted at the Seoul National University Hospital Gangnam Center, Korea.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Preventable Cancers Caused by Infection in Korea From 2015 to 2030.Journal of Korean medical science · 2025Pooled it
- Genome-wide association study implicates the role of TBXAS1 in the pathogenesis of depressive symptoms among the Korean population.Translational psychiatry · 2024Pooled it
- Leveraging deep phenotyping from health check-up cohort with 10,000 Korean individuals for phenome-wide association study of 136 traits.Scientific reports · 2022Pooled it
- Metabolic Syndrome and Its Components Are Associated with Closed-Type Endoscopic Atrophic Gastritis in a Large Screening Cohort.Digestive diseases and sciences · 2026Article
- Retinal Arteriosclerosis in a Large Health Screening Cohort: Associations with Systemic Vascular Comorbidities and Stroke in Young Adults.Biomedicines · 2026Article
- Discrepancy between Genetically Predicted and Observed Alcohol Intake and Its Impact on Gastric Cancer Susceptibility.Cancer research and treatment · 2026Article
- Occupational and Environmental Health Screening Cohort of Yangsan Korea (OEC-YK): 2012-2023.Annals of occupational and environmental medicine · 2025Article
- Association of Multiple-trait Polygenic Risk Score with Obesity and Cardiometabolic Diseases in Korean Population.Genomics, proteomics & bioinformatics · 2025Article
- External Testing of a Deep Learning Model for Lung Cancer Risk from Low-Dose Chest CT.Radiology · 2025Article
- Epidemiology and risk factors of glaucoma in a comprehensive health screening baseline report from the Gangnam Eye Cohort Study.Scientific reports · 2025Article
- Influence of lifestyle risk factors and genetic predisposition on metabolic syndrome risk in Korean adults.Scientific reports · 2025Article
- Estimation of Population Attributable Fraction by Hormone and Reproductive Factors on Female Cancer in the Republic of Korea, 2015 to 2030.Cancer research and treatment · 2025Article
- Artificial Intelligence-Driven Biological Age Prediction Model Using Comprehensive Health Checkup Data: Development and Validation Study.JMIR aging · 2025Article
- Vision transformer based interpretable metabolic syndrome classification using retinal Images.NPJ digital medicine · 2025Article
- Genome wide interaction study of genetic variants associated with lung function decline.Scientific reports · 2025Article
- Article
- Preventable cancer cases and deaths attributable to deficit of physical activity in Korea from 2015 to 2030.Epidemiology and health · 2025Article
- Associations between Disc Hemorrhage and Primary Open-Angle Glaucoma Based on Genome-Wide Association and Mendelian Randomization Analyses.Biomedicines · 2024Article
- Clonal hematopoiesis in LGI1-antibody encephalitis.Annals of clinical and translational neurology · 2024Article
- External Testing of a Deep Learning Model to Estimate Biologic Age Using Chest Radiographs.Radiology. Artificial intelligence · 2024Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Health and Prevention Enhancement (H-PEACE) study was designed to investigate the association of diagnostic imaging results, biomarkers and the predisease stage of non-communicable diseases (NCDs), such as malignancies and metabolic diseases, in an average-risk population in Korea.
participantsThis study enrolled a large-scale retrospective cohort at the Healthcare System Gangnam Center, Seoul National University Hospital, from October 2003 to December 2014. FINDINGS TO DATE: The baseline and follow-up information collected in the predisease stage of NCDs allows for evaluation of an individual's potential NCD risk, which is necessary for establishing personalised prevention strategies. A total of 91 336 health examinees were included in the cohort, and we repeatedly measured and collected information for 50.9% (n=46 484) of the cohort members. All participants completed structured questionnaires (lifestyle, medical history, mini-dietary assessment index, sex-specific variables and psychiatric assessment), doctors' physical examinations, laboratory blood and urine tests and digital chest X-ray imaging. For participants with available data, we also obtained information on specific diagnostic variables using advanced diagnostic tests, including coronary CT for coronary calcium scores, colonoscopy and brain MRI. Furthermore, 17 455 of the participants who provided informed consent and donated blood samples were enrolled into the Gene-environmental interaction and phenotype study, a subcohort of the H-PEACE, from October 2013, and we analysed genome-wide single-nucleotide polymorphism array data for 6579 of these blood samples. FUTURE PLANS: The data obtained from this cohort will be used to facilitate advanced and accurate diagnostic techniques related to NCDs while considering various phenotypes. Potential collaborators can access the dataset after receiving approval from our institutional review board. Applications can be submitted on the study homepage (http://en-healthcare.snuh.org/HPEACEstudy).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.