ArticleJournal of the American Heart Association2018
Sex Differences in the Impact of Body Mass Index on the Risk of Future Atrial Fibrillation: Insights From the Longitudinal Population-Based Tromsø Study.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Weight change and the risk of incident atrial fibrillation: a systematic review and meta-analysis.Heart (British Cardiac Society) · 2019Pooled it
- Modifiable Risk Factors in Atrial Fibrillation: Clinical Implications and Pathophysiological Insights.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Review
- Sex differences in adiposity and hemodynamic parameters as cardiovascular risk indicators among South African university staff: a descriptive cross-sectional study.BMC cardiovascular disorders · 2025Article
- Long-term pulse pressure trajectories and risk of incident atrial fibrillation: the Tromsø Study.European heart journal · 2025Article
- Article
- Metabolically 'extremely unhealthy' obese and non-obese patients with diabetes and the risk of cardiovascular events: a French nationwide cohort study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- JCS/JHRS 2020 Guideline on Pharmacotherapy of Cardiac Arrhythmias.Journal of arrhythmia · 2022Article
- Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation.Cell reports. Medicine · 2022Article
- Sex Differences in Adiposity and Cardiovascular Diseases.International journal of molecular sciences · 2022Review
- Women and atrial fibrillation.Journal of cardiovascular electrophysiology · 2021Review
- Characterising the relationships between physiological indicators and all-cause mortality (NHANES): a population-based cohort study.The lancet. Healthy longevity · 2021Observational
- The impact of weight loss related to risk of new-onset atrial fibrillation in patients with type 2 diabetes mellitus treated with sodium-glucose cotransporter 2 inhibitor.Cardiovascular diabetology · 2021Observational
- Prevalence and incidence rates of atrial fibrillation in Norway 2004-2014.Heart (British Cardiac Society) · 2021Article
- Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart.Cardiovascular research · 2021Review
- Race, Body Mass Index, and the Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.Journal of the American Heart Association · 2021Article
- Genetically-determined body mass index and the risk of atrial fibrillation progression in men and women.PloS one · 2021Article
- Sex Differences and Regulatory Actions of Estrogen in Cardiovascular System.Frontiers in physiology · 2021Review
- Sex differences in cardiometabolic disorders.Nature medicine · 2019Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtrial fibrillation (AF) prevalence is increasing, and body mass index (BMI) is a risk factor for AF. However, sex differences in the impact of BMI on AF risk have not been fully elucidated. METHODS AND
resultsData from the fourth survey (1994-1995) of the Tromsø Study (Norway) were used to investigate the association of single-measurement BMI on future AF risk. To analyze the influence of BMI changes on AF risk, data from individuals who attended the third and fourth study surveys were used. AF diagnosis was derived from record linkage and end point adjudication. Cox regression analysis was conducted using fractional polynomials of BMI and BMI change with models adjusted for age, baseline BMI (change analyses), risk factors, comorbidities, and antihypertensive medications.Data were available for 24 799 individuals from the fourth survey (mean age, 45.5±14.2 years; 52.9% women). Over 15.7±5.5 years, 811 women (6.2%) and 918 men (7.9%) developed AF. In men, lower BMI decreased AF risk and higher BMI increased risk (hazard ratios [95% confidence intervals] for BMI 18 or 40 kg/m
conclusionsWithin a population cohort, BMI was positively associated with AF risk. Change in BMI over time influenced AF risk in both men and women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.