Evidence map›Paper›PMID 29673479›Full record

ReviewNeuron2018

Genetic Dissection of Neural Circuits: A Decade of Progress.

Liqun Luo, Edward M Callaway, Karel Svoboda

Erratum issuedAbstract readReview
In one paragraph

Review in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 230 papers.

0numbers the graph read from it
0cells of the map it votes in
230citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

230 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Afterimages drive a shared visual motion-reversal illusion inbioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Neurodatascience: Past, Present, and Future.Data science in science · 2026
    Article
  18. ATF3-based peripheral neural tract tracing.Frontiers in neuroanatomy · 2026
    Article
  19. Article
  20. Review

170 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Liqun LuoDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Edward M CallawaySystems Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: callaway@salk.edu.
Karel SvobodaHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA 20147, USA.

Funding

Molecular SignaturesU19MH114831 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI DONG, HONG-WEI · 2017 to 2021
$24.6M
Local Connections of Inhibitory Cortical NeuronsR01MH063912 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CALLAWAY, EDWARD M · 2001 to 2020
$8.4M
Organization and Function of Visual Cortical Feedback SystemsR01EY022577 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI EDWARD M CALLAWAY · 2012 to 2026
$8.0M
Mosaic Analysis with Double Markers in MiceR01NS050835 · NINDS · STANFORD UNIVERSITY · PI LIQUN LUO · 2005 to 2026
$7.3M
Neuromodulation of Brain StatesR01NS104698 · NINDS · STANFORD UNIVERSITY · PI LUO, LIQUN · 2018 to 2022
$3.3M
Methodologically-Integrated Approaches Linking Cell Types to Neural Circuits and FunctionR21NS105129 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CALLAWAY, EDWARD M · 2017 to 2018
$534k
NEI NIH HHS R01 EY022577NIMH NIH HHS R01 MH063912NIMH NIH HHS U19 MH114831NINDS NIH HHS R01 NS050835NINDS NIH HHS R01 NS104698NINDS NIH HHS R21 NS105129
6 · The paper itself

Abstract

Tremendous progress has been made since Neuron published our Primer on genetic dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical, neurophysiological, and perturbation studies have been carried out in a multitude of invertebrate and vertebrate organisms, linking neurons and circuits to behavioral functions. New methods allow systematic classification of cell types and provide genetic access to diverse neuronal types for studies of connectivity and neural coding during behavior. Here we evaluate key advances over the past decade and discuss future directions.

Indexed as

AnimalsBrainBrain ChemistryHumansNerve NetNeural PathwaysNeuronsOptogeneticsTime Factors

Identifiers

PMID29673479
PMCPMC5912347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.