Evidence map›Paper›PMID 29673384›Full record

ArticleRadiation oncology (London, England)2018

Prognostic factors of radiation dermatitis following passive-scattering proton therapy for breast cancer.

Xiaoying Liang, Julie A Bradley, Dandan Zheng, Michael Rutenberg, Daniel Yeung, Nancy Mendenhall, Zuofeng Li

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoying LiangDepartment of Radiation Oncology, University of Florida, Gainesville, FL, USA. xliang@floridaproton.org.ORCID http://orcid.org/0000-0002-6688-1045
Julie A BradleyDepartment of Radiation Oncology, University of Florida, Gainesville, FL, USA.
Dandan ZhengDepartment of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.
Michael RutenbergDepartment of Radiation Oncology, University of Florida, Gainesville, FL, USA.
Daniel YeungDepartment of Radiation Oncology, University of Florida, Gainesville, FL, USA.
Nancy MendenhallDepartment of Radiation Oncology, University of Florida, Gainesville, FL, USA.
Zuofeng LiDepartment of Radiation Oncology, University of Florida, Gainesville, FL, USA.
University of Florida · USUniversity of Nebraska Medical Center · US

Funding

UFHPTI Research/education fund
6 · The paper itself

Abstract

backgroundTo identify prognostic factors for grade 3 radiation dermatitis following passive-scattering proton therapy for breast cancer.

methodsThis retrospective study included data on 23 (11 post-mastectomy and 12 post-lumpectomy) breast cancer patients who underwent proton therapy with the passive scattering technique in our institute from 2012 to 2016. Each patient received 50-50.4 cobalt Gy equivalent (CGE) at 1.8 or 2 CGE per daily fraction. Logistic regression analysis was performed to identify prognostic factors for grade 3 skin toxicity. Receiver operating characteristic (ROC) curve analysis and the area under the curve (AUC) were used to evaluate the performance of the models.

results43% of the studied patients developed grade 3 radiation dermatitis. The dose-volume histogram (DVH) parameters of V52.5CGE and D10cm

conclusionIn the current study, we identified prognostic factors for grade 3 radiation dermatitis in patients treated with passive-scattering proton therapy for breast cancer. This study provides promising tool for identifying high risk patients for whom treatment plan adjustment could be done to reduce the risk of radiation-induced grade 3 skin toxicity.

Indexed as

Breast NeoplasmsDose Fractionation, RadiationFemaleFollow-Up StudiesHumansPrognosisProton TherapyRadiodermatitisRetrospective StudiesROC CurveBreast cancerLogistic regression analysisPassive-scattering proton therapyRadiation dermatitis

Identifiers

PMID29673384
PMCPMC5909216
OpenAlexW2805284475

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.