Evidence map›Paper›PMID 29673383›Full record

ArticleRadiation oncology (London, England)2018

Radiotherapy for calcaneodynia, achillodynia, painful gonarthrosis, bursitis trochanterica, and painful shoulder syndrome - Early and late results of a prospective clinical quality assessment.

Oliver Micke, Eyup Ugrak, Stefan Bartmann, Irenaeus A Adamietz, Ulrich Schaefer, Rebecca Bueker, Klaus Kisters, M Heinrich Seegenschmiedt, Khashayar Fakhrian, Ralph Muecke

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04424628 (Three vs Six Gy in Gonarthrosis and Coxarthrosis. Non Inferiority Study), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04424628 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Three vs Six Gy in Gonarthrosis and Coxarthrosis. Non Inferiority Study

TypeinterventionalSponsorFundacion GenesisCareRan2019 to 2023Enrolled338ConditionsGonarthrosis, CoxarthrosisArmsLow dose radiotherapy A, Low dose radiotherapy B
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Implementing a low-dose radiation therapy program for musculoskeletal pain disorders: tips, tricks, and essentials for clinical researchers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  7. Radiotherapy for painful shoulder syndrome: a retrospective evaluation.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  8. Review
  9. Low-dose Radiation Therapy (LDRT) in Managing Osteoarthritis: A Comprehensive Review.Current therapeutic research, clinical and experimental · 2025
    Review
  10. Review
  11. Low-dose radiotherapy for greater trochanteric pain syndrome-a single-centre analysis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  12. Non-Oncological Radiotherapy: A Review of Modern Approaches.Journal of personalized medicine · 2022
    Review
  13. Treatment of benign tumours and related pathologies with radiotherapy: experience of the General Hospital of Mexico.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Article
  14. Long-term effect and prognostic factors of a low-dose radiotherapy of painful plantar calcaneal spurs : A retrospective unicenter study.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  15. Low-dose radiotherapy for painful osteoarthritis of the elderly: A multicenter analysis of 970 patients with 1185 treated sites.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021
    Article
  16. Review
  17. Article
  18. Radiotherapy for osteoarthritis-an analysis of 295 joints treated with a linear accelerator.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  19. Article
  20. Re-irradiation for osteoarthritis-retrospective analysis of 217 joints.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Oliver MickeDepartment of Radiotherapy and Radiation Oncology, Franziskus Hospital Bielefeld, Kiskerstrasse 26, D-33615, Bielefeld, Germany. oliver.micke@franziskus.de.ORCID http://orcid.org/0000-0002-3812-9251
Eyup UgrakDepartment of Internal Medicine, St. Anna Hospital, Herne, Germany.
Stefan BartmannDepartment of Urology, Lippe Hospital, Detmold, Germany.
Irenaeus A AdamietzDepartment of Radiotherapy and Radiation Oncology, Marien Hospital Herne, Ruhr University Bochum, Bochum, Germany.
Ulrich SchaeferDepartment of Radiotherapy, Lippe Hospital, Lemgo, Germany.
Rebecca BuekerDepartment of Radiotherapy, Lippe Hospital, Lemgo, Germany.
Klaus KistersDepartment of Internal Medicine, St. Anna Hospital, Herne, Germany.
M Heinrich SeegenschmiedtCenter for Radiotherapy, Hamburg, Germany.
Khashayar FakhrianDepartment of Radiotherapy and Radiation Oncology, Marien Hospital Herne, Ruhr University Bochum, Bochum, Germany.
Ralph MueckeDepartment of Radiotherapy and Radiation Oncology, Marien Hospital Herne, Ruhr University Bochum, Bochum, Germany.
Klinikum Lippe · DEUniversitätsklinik Marien Hospital Herne · DESt. Anna Hospital · DEFrancis Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this prospective clinical quality assessment was to evaluate the short-term and long-term efficacy of low dose radiotherapy (RT) for calcaneodynia, achillodynia, painful gonarthrosis, painful bursitis trochanterica, and painful shoulder syndrome.

methodsBetween October 2011 and October 2013, patients with calcaneodynia, achillodynia, painful gonarthrosis, painful bursitis trochanterica, and painful shoulder syndrome were recruited for this prospective clinical quality assessment. Single doses of 0.5-1.0 Gy and a total dose of 6.0 Gy per series were used. Pain was measured before and directly after RT (early response) with a visual analogue scale (VAS). Additionally, pain relief was measured with the four-scale pain score according to "von Pannewitz" (VPS) immediately at the end of RT and during follow-up. Within this context we defined a good response as complete pain relief and markedly improved. The assessment of the long-term efficacy was carried out by a telephone survey.

results703 evaluable patients (461 female, 242 male) with a mean age of 63.2 years (28-96) were recruited for this prospective clinical quality assessment. In 254 patients RT was performed with the linear accelerator, 449 patients received orthovoltage radiotherapy. After a median follow-up of 33 months (3-60) 437 patients could be reached for evaluation of follow up results. The mean VAS value before treatment was 6.63 (1.9-10) and immediately on completion of RT 4.51 (0-10) (p < 0,001). Concerning the VPS immediately on completion of RT, a good response could be achieved in 264/703 patients (37.6%), and with the follow up in 255/437 patients (58.4%) (p < 0.001). Only in patients with gonarthrosis we could not observe a significantly improved long-term success in comparison to the results immediately after RT (30.2% versus 29.9%).

conclusionLow dose RT is a very effective treatment for the management of calcaneodynia, achillodynia, painful gonarthrosis, painful bursitis trochanterica, and painful shoulder syndrome. Due to the delayed onset of analgesic effects low dose RT results in a significantly improved long-term efficacy in comparison to the results immediately after RT particularly in patients with calcaneodynia, achillodynia, bursitis trochanterica, and shoulder syndrome.

Indexed as

Achilles TendonAdultAgedAged, 80 and overBursitisCalcaneusFemaleFollow-Up StudiesFoot DiseasesHumansMaleMiddle AgedOsteoarthritis, KneePain MeasurementProspective StudiesRadiotherapy DosageBenign diseasesBursitis trochantericaCalcaneodyniaGonarthrosisRadiotherapyShoulder syndrome

Identifiers

PMID29673383
PMCPMC5907721
OpenAlexW2804812851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.