Evidence map›Paper›PMID 29673335›Full record

ArticleBMC cancer2018

Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China.

Fei He, Ren-Dong Xiao, Tao Lin, Wei-Min Xiong, Qiu-Ping Xu, Xu Li, Zhi-Qiang Liu, Bao-Chang He, Zhi-Jian Hu, Lin Cai

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  11. Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Review
  12. Enzymology of vertebrate carotenoid oxygenases.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Fei HeDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Ren-Dong XiaoDepartment of Thoracic Surgery, The first affiliated hospital of Fujian Medical University, Fuzhou, 350005, China.
Tao LinDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Wei-Min XiongDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Qiu-Ping XuDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Xu LiDepartment of Thoracic Surgery, The first affiliated hospital of Fujian Medical University, Fuzhou, 350005, China.
Zhi-Qiang LiuDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Bao-Chang HeDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Zhi-Jian HuDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Lin CaiDepartment of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, 350108, China. x117x@163.com.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CN

Funding

Fujian Provincial Natural Science Foundation Project 2016J01355National Natural Science Foundation of China 81402738the projects of environmental science and technology of Fujian Province 2015R012
6 · The paper itself

Abstract

backgroundWe investigated whether BCMO1 variants and dietary patterns are associated with lung cancer risk.

methodsCase-control study including 1166 lung cancer cases and 1179 frequency matched controls was conducted for three BCMO1 variants (rs6564851, rs12934922, and rs7501331) and four dietary patterns were investigated. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs).

resultsThe rs6564851, rs12934922, and rs7501331 were not found to be associated with lung cancer risk (P > 0.05). In multivariable-adjusted models, compared to the lowest quartile of the score on the "fruits and vegetables" pattern, the highest quintile was associated with a 78.4% decreased risk (OR

conclusionsWe did not observe associations of BCMO1 variants and lung cancer. Diets rich in fruits and vegetables may be protective against lung cancer.

Indexed as

Feeding BehaviorPolymorphism, GeneticAgedAllelesbeta-Carotene 15,15'-MonooxygenaseCase-Control StudiesChinaFemaleGenotypeHumansLung NeoplasmsMaleMiddle AgedOdds RatioPolymorphism, Single NucleotideRisk AssessmentBCO1 protein, humanbeta-Carotene 15,15'-MonooxygenaseBCMO1 polymorphismsCase-control studyChineseDietary patternsPrimary lung cancer

Identifiers

PMID29673335
PMCPMC5909209
OpenAlexW2805184727

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.