Evidence map›Paper›PMID 29673319›Full record

ArticleBMC microbiology2018

Carbapenemase-producing Enterobacteriaceae in Mexico: report of seven non-clonal cases in a pediatric hospital.

Alejandra Aquino-Andrade, Jocelin Merida-Vieyra, Eduardo Arias de la Garza, Patricia Arzate-Barbosa, Agustín De Colsa Ranero

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Isolation and Identification of Multidrug-ResistantPathogens (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Dissemination ofFrontiers in microbiology · 2021
    Article
  16. Article
  17. Article
  18. The Global Ascendency of OXA-48-Type Carbapenemases.Clinical microbiology reviews · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alejandra Aquino-AndradeMolecular Microbiology Laboratory, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Insurgentes Cuicuilco, ZC, 04530, Coyoacán Mexico City, Mexico.
Jocelin Merida-VieyraMolecular Microbiology Laboratory, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Insurgentes Cuicuilco, ZC, 04530, Coyoacán Mexico City, Mexico.
Eduardo Arias de la GarzaPediatric Infectious Disease Department, Instituto Nacional de Pediatria, Mexico City, Mexico.
Patricia Arzate-BarbosaClinical Bacteriology Laboratory, Instituto Nacional de Pediatria, Mexico City, Mexico.
Agustín De Colsa RaneroMolecular Microbiology Laboratory, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Insurgentes Cuicuilco, ZC, 04530, Coyoacán Mexico City, Mexico. agustin.decolsa@infecto.mx.ORCID 0000-0001-6323-6668
Instituto Nacional de Pediatria · MXUniversidad Insurgentes · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarbapenemases-producing Enterobacteriaceae (CPE) are a worldwide public health emergency. In Mexico, reports of CPE are limited, particularly in the pediatric population. Here, we describe the clinical, epidemiological, and molecular characteristics of seven consecutive cases in a third-level pediatric hospital in Mexico City over a four-month period during 2016.

resultsThe Enterobacteriaceae identified were three Escherichia coli strains (producing OXA-232, NDM-1 and KPC-2), two Klebsiella pneumoniae strains (producing KPC-2 and NDM-1), one Klebsiella oxytoca strain producing OXA-48 and one Enterobacter cloacae strain producing NDM-1. The majority of patients had underlying disesases, three were immunocompromised, and three had infections involved the skin and soft tissues. Half patients died as a result of CPE infection.

conclusionsThis study represents the first report of E. coli ST131-O25b clone producing NDM-1 in Latin America. In addition, this study is the first finding of K. oxytoca producing OXA-48 and E. coli producing OXA-232 in Mexican pediatric patients.

Indexed as

Adolescentbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeChildChild, PreschoolEnterobacter cloacaeEnterobacteriaceae InfectionsEscherichia coliFemaleGenotypeHospitals, PediatricHumansInfantKlebsiella oxytocaKlebsiella pneumoniaeLatin Americabeta-lactamase KPC-2beta-lactamase KPC-2, Klebsiella pneumoniaebeta-lactamase NDM-1beta-LactamasesoxacillinaseCarbapenemase-producing EnterobacteriaceaeKPC-2MexicoNDM-1OXA-232OXA-48Pediatrics

Identifiers

PMID29673319
PMCPMC5907697
OpenAlexW2805660672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.