Evidence map›Paper›PMID 29672871›Full record

Observational studyClinical cardiology2018

Sex differences in the contemporary management of HIV patients admitted for acute myocardial infarction.

Gbolahan O Ogunbayo, Katrina Bidwell, Naoki Misumida, Le Dung Ha, Ahmed Abdel-Latif, Claude S Elayi, Susan Smyth, Adrian W Messerli

Open access · bronzeAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cardiac Catheterization Procedures in Patients with HIV: A Retrospective Analysis.Journal of cardiovascular development and disease · 2021
    Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gbolahan O OgunbayoDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.ORCID http://orcid.org/0000-0002-4140-8067
Katrina BidwellDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.
Naoki MisumidaDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.
Le Dung HaDepartment of Internal Medicine, Rochester General Hospital, Rochester, New York.
Ahmed Abdel-LatifDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.
Claude S ElayiDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.
Susan SmythDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.
Adrian W MesserliDivision of Cardiology, Department of Internal Medicine, University of Kentucky, Lexington.
University of Kentucky · USRochester General Hospital · US

Funding

The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2012 to 2017
$13.7M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
Role of Bioactive Lipids in Stem Cell Mobilization and Homing in Cardiac IschemiaR56HL124266 · NHLBI · UNIVERSITY OF KENTUCKY · PI ABDEL-LATIF, AHMED · 2014 to 2014
$375k
NCATS NIH HHS UL1 TR000117NHLBI NIH HHS R56 HL124266NIGMS NIH HHS P20 GM103527
6 · The paper itself

Abstract

backgroundStudies have reported sex differences in the management of patients with acute myocardial infarction (AMI) in the general population. This observational study is designed to evaluate whether sex differences exist in the contemporary management of human immunodeficiency virus (HIV) patients admitted for diagnosis of AMI. HYPOTHESIS: There is no difference in management of HIV patients with AMI.

methodsUsing the National Inpatient Sample database, we identified patients with a primary diagnosis of AMI and a secondary diagnosis of HIV. We described baseline characteristics and outcomes using NIS documentation. Our primary areas of interest were revascularization and mortality.

resultsAmong 2 977 387 patients presenting from 2010 to 2014 with a primary diagnosis of AMI, 10907 (0.4%) had HIV (mean age, 54.1 ± 9.3 years; n = 2043 [18.9%] female). Females were younger, more likely to be black, and more likely to have hypertension, diabetes, obesity, and anemia. Although neither males nor females were more likely to undergo coronary angiography in multivariate analysis, revascularization was performed less frequently in females than in males (45.4% vs 62.7%; P < 0.01), driven primarily by lower incidence of PCI. In a multivariate model, females were less likely to undergo revascularization (OR: 0.59, 95% CI: 0.45-0.78, P < 0.01), a finding driven solely by PCI (OR: 0.64, 95% CI: 0.49-0.83, P < 0.01). All-cause mortality was similar in both groups.

conclusionsAMI was more common in males than females with HIV. Females with HIV were more likely to be younger and black and less likely to be revascularized by PCI.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsBlack or African AmericanChi-Square DistributionComorbidityCoronary AngiographyCoronary Artery BypassDatabases, FactualFemaleHealthcare DisparitiesHealth Status DisparitiesHIV InfectionsHumansAcute Myocardial InfarctionHuman Immunodeficiency VirusSex Differences

Identifiers

PMID29672871
PMCPMC6489827
OpenAlexW2800485797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.