Evidence map›Paper›PMID 29672822›Full record

Trial reportBritish journal of haematology2018

Identification of novel diagnostic biomarkers for deep venous thrombosis.

Ashfaque A Memon, Kristina Sundquist, Mirnabi PirouziFard, Johan L Elf, Karin Strandberg, Peter J Svensson, Jan Sundquist, Bengt Zöller

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in British journal of haematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Transcriptome Analysis IdentifiedJournal of the American Heart Association · 2025
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  15. Proteomics in thrombosis research.Research and practice in thrombosis and haemostasis · 2022
    Article
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  17. Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Ashfaque A MemonCentre for Primary Health Care Research, Department of Clinical Sciences, Lund University/Skåne University Hospital, Malmö, Sweden.ORCID 0000-0002-1081-3553
Kristina SundquistCentre for Primary Health Care Research, Department of Clinical Sciences, Lund University/Skåne University Hospital, Malmö, Sweden.
Mirnabi PirouziFardCentre for Primary Health Care Research, Department of Clinical Sciences, Lund University/Skåne University Hospital, Malmö, Sweden.
Johan L ElfDepartment of Coagulation Disorders, Skåne University Hospital, Lund University, Lund, Sweden.
Karin StrandbergDepartment of Coagulation Disorders, Skåne University Hospital, Lund University, Lund, Sweden.
Peter J SvenssonDepartment of Coagulation Disorders, Skåne University Hospital, Lund University, Lund, Sweden.
Jan SundquistCentre for Primary Health Care Research, Department of Clinical Sciences, Lund University/Skåne University Hospital, Malmö, Sweden.
Bengt ZöllerCentre for Primary Health Care Research, Department of Clinical Sciences, Lund University/Skåne University Hospital, Malmö, Sweden.
Lund University · SE

Funding

Neighborhoods and Coronary Disease: Exploring Mechanisms and Improving MethodsR01HL116381 · NHLBI · LUNDS UNIVERSITET · PI SUNDQUIST, KRISTINA · 2014 to 2017
$1.9M
NHLBI NIH HHS R01 HL116381
6 · The paper itself

Abstract

The combination of a negative D-dimer and a Wells score can rule out, but not confirm, a diagnosis of deep venous thrombosis (DVT). We aimed to identify new diagnostic biomarkers for DVT and to investigate their relationship with hypercoagulability markers [D-dimer and activated protein C-protein C inhibitor (APC-PCI) complex]. We screened 92 cardiovascular-specific proteins in plasma samples from 45 confirmed DVT patients and 45 age- and sex-matched non-DVT patients selected from a prospective multicentre diagnostic management study (SCORE) by Proseek Multiplex CVDIII

Indexed as

AdultAgedAged, 80 and overAntigens, CDBiomarkersCysteine EndopeptidasesFemaleFibrin Fibrinogen Degradation ProductsHumansInterleukin-1 Receptor-Like 1 ProteinMaleMiddle AgedOsteopontinProtein C InhibitorP-SelectinReceptors, TransferrinAntigens, CDBiomarkersbleomycin hydrolaseCD71 antigenCysteine EndopeptidasesFibrin Fibrinogen Degradation Productsfibrin fragment DIL1RL1 protein, humanInterleukin-1 Receptor-Like 1 ProteinOsteopontinProtein C InhibitorP-SelectinReceptors, TransferrinSERPINA5 protein, humanSPP1 protein, humanvon Willebrand FactorAPC-PCIcoagulationD-dimerdeep venous thrombosisdiagnostic biomarkers

Identifiers

PMID29672822
PMCPMC5918233
OpenAlexW2800007737

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.