ArticlePloS one2018
Stress pre-conditioning with temperature, UV and gamma radiation induces tolerance against phosphine toxicity.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Asymmetric Micro-Evolutionary Responses in a Warming World: Heat-Driven Adaptation Enhances Metal Tolerance in a Planktonic Rotifer, but Not Vice Versa.Global change biology · 2025Article
- Protective multi-stressor interactions in the Anthropocene: Key considerations for investigating cross-tolerance in a conservation context.Conservation physiology · 2025Article
- Long-Term Survivability of TardigradeLife (Basel, Switzerland) · 2024Article
- Pesticidal Toxicity of Phosphine and Its Interaction with Other Pest Control Treatments.Current issues in molecular biology · 2023Review
- Mechanisms tailoring the expression of heat shock proteins to proteostasis challenges.The Journal of biological chemistry · 2022Review
- Article
- Harnessing the potential of cross-protection stressor interactions for conservation: a review.Conservation physiology · 2021Article
- Increasing temperatures accentuate negative fitness consequences of a marine parasite.Scientific reports · 2020Article
- Antidotal Action of Some Gold(I) Complexes toward Phosphine Toxicity.Chemical research in toxicology · 2019Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phosphine is the only general use fumigant for the protection of stored grain, though its long-term utility is threatened by the emergence of highly phosphine-resistant pests. Given this precarious situation, it is essential to identify factors, such as stress preconditioning, that interfere with the efficacy of phosphine fumigation. We used Caenorhabditis elegans as a model organism to test the effect of pre-exposure to heat and cold shock, UV and gamma irradiation on phosphine potency. Heat shock significantly increased tolerance to phosphine by 3-fold in wild-type nematodes, a process that was dependent on the master regulator of the heat shock response, HSF-1. Heat shock did not, however, increase the resistance of a strain carrying the phosphine resistance mutation, dld-1(wr4), and cold shock did not alter the response to phosphine of either strain. Pretreatment with the LD50 of UV (18 J cm-2) did not alter phosphine tolerance in wild-type nematodes, but the LD50 (33 J cm-2) of the phosphine resistant strain (dld-1(wr4)) doubled the level of resistance. In addition, exposure to a mild dose of gamma radiation (200 Gy) elevated the phosphine tolerance by ~2-fold in both strains.
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Registered trials
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