ReviewJournal of applied physiology (Bethesda, Md. : 1985)2018
Diaphragm plasticity in aging and disease: therapies for muscle weakness go from strength to strength.
Review in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05709054 (The Effect of Manual Therapy Techniques on the Mobility of the Diaphragm in People With Asthma), which is not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Manual Therapy Techniques on the Mobility of the Diaphragm in People With Asthma: Protocol for a Randomized Controlled Trial
Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Sex-Specific Cut-off Values for Respiratory Muscle Strength in Older Women: Screening Implications for Respiratory Sarcopenia.Journal of Korean medical science · 2026Article
- Creatine supplementation and respiratory muscle function in health and disease: translational insights from human to mouse.ERJ open research · 2026Article
- Diaphragmatic Muscle Thickness: A Complementary Tool in Assessing Lung Involvement in Patients with Systemic Sclerosis.Medical sciences (Basel, Switzerland) · 2026Observational
- Association between diaphragm thickness and postoperative complications in elderly patients with non-small-cell lung cancer.Surgery today · 2026Article
- Cholesterol-Lowering Treatment Suppresses Neuromuscular Transmission Via Presynaptic Mechanism at the Mouse Diaphragm Muscle.Neurochemical research · 2025Article
- Relationship between hand grip strength and lung function among older adults in Korea: Secondary analysis of the Korea National Health and Nutrition Examination Survey.Journal of Korean gerontological nursing · 2025Article
- Diaphragm thickness and ICU admission risk in elderly COVID-19 patients: a CT-based analysis.BMC pulmonary medicine · 2025Article
- A Novel Research Paradigm for Sarcopenia of Limb Muscles: Lessons From the Perpetually Working Diaphragm's Anti-Aging Mechanisms.Journal of cachexia, sarcopenia and muscle · 2025Article
- Chronic sustained hypoxia alters the pattern of diaphragm electrical activity in anaesthetized rats.Experimental physiology · 2025Article
- The systemic inflammation response index as risks factor for all-cause and cardiovascular mortality among individuals with respiratory sarcopenia.BMC pulmonary medicine · 2025Article
- Effects of external diaphragm pacing combined with repetitive peripheral magnetic stimulation of the phrenic nerve on respiratory function in stroke patients.Frontiers in medicine · 2025Article
- Evaluating Respiratory Muscle Strength in Sarcopenia Screening among Older Men in South Korea: A Retrospective Analysis.The world journal of men's health · 2024Article
- Diaphragm Ultrasound in Different Clinical Scenarios: A Review with a Focus on Older Patients.Geriatrics (Basel, Switzerland) · 2024Review
- Ultrasonic Evaluation of Diaphragm in Patients with Systemic Sclerosis.Journal of personalized medicine · 2023Article
- The effect of manual therapy on diaphragm function in adults with asthma: Protocol for a randomized controlled trial.F1000Research · 2023Article
- Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia.International journal of environmental research and public health · 2022Article
- The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy.Nature communications · 2022Article
- Validity of Diaphragm Volume Measurements Using Three-Dimensional Computed Tomography.Juntendo Iji zasshi = Juntendo medical journal · 2022Article
- Waist-To-Hip Ratio Predicts Abnormal Overnight Oximetry in Men Independent of Body Mass Index.Frontiers in cardiovascular medicine · 2021Article
- Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment.The journal of nutrition, health & aging · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
Abstract
The diaphragm is the main inspiratory muscle and is required to be highly active throughout the life span. The diaphragm muscle must be able to produce and sustain various behaviors that range from ventilatory to nonventilatory such as those required for airway maintenance and clearance. Throughout the life span various circumstances and conditions may affect the ability of the diaphragm muscle to generate requisite forces, and in turn the diaphragm muscle may undergo significant weakness and dysfunction. For example, hypoxic stress, critical illness, cancer cachexia, chronic obstructive pulmonary disorder, and age-related sarcopenia all represent conditions in which significant diaphragm muscle dysfunction exits. This perspective review article presents several interesting topics involving diaphragm plasticity in aging and disease that were presented at the International Union of Physiological Sciences Conference in 2017. This review seeks to maximize the broad and collective research impact on diaphragm muscle dysfunction in the search for transformative treatment approaches to improve the diaphragm muscle health during aging and disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.