ArticleJournal of applied physiology (Bethesda, Md. : 1985)2018
Resistive and elastic work of breathing in older and younger adults during exercise.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Ventilatory limitation to exercise in patients with HFpEF and obesity: No room to breathe.Respiratory physiology & neurobiology · 2026Trial
- A comparison of the neuromuscular, cardiopulmonary and muscle oxygenation responses to single- and double-leg cycling in older adults.Experimental physiology · 2026Article
- Ageing exacerbates the adverse effects of respiratory muscle fatigue on vascular function, locomotor muscle fatigue and exercise performance in males.Experimental physiology · 2026Article
- Sex differences in the work of breathing during exercise are independent of forced vital capacity in healthy adults.Experimental physiology · 2025Article
- Exertional inspiratory capacity and operating lung volumes in health: a population-based study.ERJ open research · 2025Article
- The Effect of Aerobic Training on Healthy Small Airways-A Forced Oscillation Technique Approach to Optimize Long Term Care in COPD.Journal of clinical medicine · 2025Article
- Differences of ventilatory muscle recruitment and work of breathing in COPD and interstitial lung disease: clarifications.ERJ open research · 2025Article
- Predicting parameters of airway dynamics generated from inspiratory and expiratory plethysmographic airway loops, differentiating subtypes of chronic obstructive diseases.BMJ open respiratory research · 2024Article
- Breathing a low-density gas reduces respiratory muscle force development and marginally improves exercise performance in master athletes.European journal of applied physiology · 2024Article
- Higher Work of Breathing During Exercise in Heart Failure With Preserved Ejection Fraction.Chest · 2023Article
- Impact of aging on the work of breathing during exercise in healthy men.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Acute Effects of Barbell Bouncing and External Cueing on Power Output in Bench Press Throw in Resistance-Trained Men.Frontiers in physiology · 2022Article
- An integrative approach to the pulmonary physiology of exercise: when does biological sex matter?European journal of applied physiology · 2021Review
- Broad individual immersion-scattering of respiratory compliance likely substantiates dissimilar breathing mechanics.Scientific reports · 2021Article
- Ascorbate attenuates cycling exercise-induced neuromuscular fatigue but fails to improve exertional dyspnea and exercise tolerance in COPD.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Respiratory muscle senescence in ageing and chronic lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2020Article
- Recovery process of respiratory muscle strength in patients following stroke: A Pilot Study.Physical therapy research · 2020Article
- Impaired central hemodynamics in chronic obstructive pulmonary disease during submaximal exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Exercise Ventilatory Efficiency in Older and Younger Heart Failure Patients With Preserved Ejection Fraction.Journal of cardiac failure · 2019Article
- Ventilatory constraints influence physiological dead space in heart failure.Experimental physiology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
It is unknown whether the greater total work of breathing (WOB) with aging is due to greater elastic and/or resistive WOB. We hypothesized that older compared with younger adults would exhibit a greater total WOB at matched ventilations (V̇e) during graded exercise, secondary to greater inspiratory resistive and elastic as well as expiratory resistive WOB. Older (OA: 60 ± 8 yr; n = 9) and younger (YA: 38 ± 7 yr; n = 9) adults performed an incremental cycling test to volitional fatigue. Esophageal pressure, inspiratory (IRV) and expiratory reserve volumes (ERV), expiratory flow limitation (EFL), and ventilatory variables were measured at matched V̇e (i.e., 25, 50, and 75 l/min) during exercise. The inspiratory resistive and elastic as well as expiratory resistive WOB were quantified using the Otis method. At V̇e of 75 l/min, older adults had greater %EFL and larger tidal volumes to inspiratory capacity but smaller relative IRV ( P ≤ 0.03) than younger adults. Older compared with younger adults had greater total WOB at V̇
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.