Evidence map›Paper›PMID 29672191›Full record

ArticleJournal of adolescent and young adult oncology2018

Knowledge and Beliefs About Oncofertility and Associations with Quality of Life Among Adolescent and Young Adult Survivors of Pediatric Cancer.

Andrea C Johnson, Darren Mays, Kathryn Rehberg, Aziza Shad, Kenneth P Tercyak

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of adolescent and young adult oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. BMJ open · 2026
    Article
  4. [Fertility management in breast cancer patients: current strategies and research advances].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea C Johnson1 Department of Prevention and Community Health, George Washington University Milken Institute School of Public Health , Washington, District of Columbia.
Darren Mays2 Lombardi Comprehensive Cancer Center, Georgetown University Medical Center , Washington, District of Columbia.
Kathryn Rehberg2 Lombardi Comprehensive Cancer Center, Georgetown University Medical Center , Washington, District of Columbia.
Aziza Shad3 Division of Pediatric Hematology Oncology, The Herman & Walter Samuelson Children's Hospital at Sinai, Baltimore, Maryland.
Kenneth P Tercyak2 Lombardi Comprehensive Cancer Center, Georgetown University Medical Center , Washington, District of Columbia.
Georgetown University · USGeorge Washington University · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
NCI NIH HHS P30 CA051008
6 · The paper itself

Abstract

purposeAdolescent and young adult (AYA) cancer survivors experience fertility and childrearing challenges in adulthood, but there is limited evidence on awareness, beliefs, and concerns about oncofertility in this population, needs for supportive resources, and associations with quality of life (QoL).

methodsParticipants were 69 AYAs aged 12-25 who were diagnosed with cancer at age 18 years or younger and ≥1 year cancer free, recruited from childhood cancer clinical records and support organizations. Participants completed self-report assessment of oncofertility knowledge and beliefs, information needs, and measures of QoL. Analyses examined associations between oncofertility-related variables and QoL.

resultsKnowledge and beliefs about oncofertility options were considerably low in the sample, and participants reported unmet oncofertility resource needs. In multivariable analyses, QoL was associated with beliefs valuing the importance of fertility in childhood cancer (β = 0.87, p = 0.01) and lower information needs (β = -1.19, p = 0.022).

conclusionsInfertility is a well-documented effect of childhood cancer treatment. Our findings indicate that clinical providers are a preferred source of information for AYA patients, and there is a need to address oncofertility concerns and challenges in this group. Research is needed to examine barriers to addressing fertility issues in childhood cancer treatment and ways to promote dialogue between providers and patients and their families.

Indexed as

AdolescentAdultCancer SurvivorsChildCultureFemaleFertilityHumansMaleQuality of LifeSurveys and QuestionnairesYoung Adultoncofertilityperceptionsquality of lifesupportive caresurvivorship

Identifiers

PMID29672191
PMCPMC6083203
OpenAlexW2801142647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.