ArticleAmerican journal of respiratory and critical care medicine2018
Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort.
Article in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 65 citations in OpenAlex.
- CT-based pulmonary vascular pruning and emphysema: clinical correlations and prognostic impacts in COPD.European radiology · 2026Article
- Computed tomography-derived pulmonary blood volume distribution may be modifiable in asthma.ERJ open research · 2026Article
- Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI.Journal of magnetic resonance imaging : JMRI · 2026Article
- Chest CT imaging toward personalized management of chronic obstructive pulmonary disease, asthma, and bronchiectasis: pulmonologist perspectives.Japanese journal of radiology · 2026Review
- Article
- Vascular remodeling in asthma: from mechanisms to precision medicine.Current opinion in allergy and clinical immunology · 2026Review
- Unsupervised comprehensive CT imaging clusters reveal distinct morphological phenotypes in asthma: insights from two prospective cohorts.Respiratory research · 2026Article
- Back to the future in asthma imaging: quantitative assessment and new perspectives.La Radiologia medica · 2026Review
- Does the Reversal and Normalization of Airway and Pulmonary Vascular Remodeling Accompany Asthma Remission?Chest · 2025Article
- Quantitative assessment of pulmonary blood flow redistribution in the classification of group 1 and group 4 pulmonary hypertension.Quantitative imaging in medicine and surgery · 2024Article
- Emerging multimodality imaging techniques for the pulmonary circulation.The European respiratory journal · 2024Review
- Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation.The Journal of allergy and clinical immunology · 2024Article
- Systemic Inflammation in Asthma: What Are the Risks and Impacts Outside the Airway?The journal of allergy and clinical immunology. In practice · 2024Review
- Evaluation of retrieval accuracy and visual similarity in content-based image retrieval of chest CT for obstructive lung disease.Scientific reports · 2024Article
- Children with severe asthma have substantial structural airway changes on computed tomography.ERJ open research · 2024Article
- A new approach to computed tomography measurement of airway remodelling in paediatric asthma.ERJ open research · 2024Article
- Association Between Pulmonary Vascular Volume and Cardiac Structure and Function in Patients With Atrial Fibrillation.The American journal of cardiology · 2023Article
- CT imaging determinants of persistent hypoxemia in acute intermediate-risk pulmonary embolism.Journal of thrombosis and thrombolysis · 2023Article
- Treatment Response Evaluation by Computed Tomography Pulmonary Vasculature Analysis in Patients With Chronic Thromboembolic Pulmonary Hypertension.Korean journal of radiology · 2023Article
- Quantitative Imaging Metrics for the Assessment of Pulmonary Pathophysiology: An Official American Thoracic Society and Fleischner Society Joint Workshop Report.Annals of the American Thoracic Society · 2023Article
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Authors and funding
21 authors at 13 institutions in 2 countries.
Funding
Abstract
rationaleLoss of the peripheral pulmonary vasculature, termed vascular pruning, is associated with disease severity in patients with chronic obstructive pulmonary disease.
objectivesTo determine if pulmonary vascular pruning is associated with asthma severity and exacerbations.
methodsWe measured the total pulmonary blood vessel volume (TBV) and the blood vessel volume of vessels less than 5 mm MEASUREMENTS AND MAIN
resultsCompared with healthy control subjects, patients with severe asthma had more pulmonary vascular pruning. Among those with asthma, those with poor asthma control had more pruning than those with well-controlled disease. Pruning of the pulmonary vasculature was also associated with lower percent predicted FEV
conclusionsPruning of the peripheral pulmonary vasculature is associated with asthma severity, control, and exacerbations, and with lung function and eosinophilia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.