Evidence map›Paper›PMID 29671924›Full record

ArticleHuman brain mapping2018

Effects of SYN1

Jean-François Cabana, Guillaume Gilbert, Laurent Létourneau-Guillon, Dima Safi, Isabelle Rouleau, Patrick Cossette, Dang Khoa Nguyen

Open access · bronzeAbstract read
In one paragraph

Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The different clinical facets ofFrontiers in cell and developmental biology · 2022
    Article
  5. Effects of SYN1Human brain mapping · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jean-François CabanaCentre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec.ORCID 0000-0003-0579-5378
Guillaume GilbertCentre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec.
Laurent Létourneau-GuillonCentre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec.
Dima SafiUniversité du Québec à Trois-Rivières (UQTR), Trois-Rivières, Québec.
Isabelle RouleauCentre de Recherche du CHUM (CRCHUM), Montréal, Québec.
Patrick CossetteCentre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec.
Dang Khoa NguyenCentre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec.
Centre Hospitalier de l’Université de Montréal · CAPhilips (Canada) · CAUniversité du Québec à Montréal · CAUniversité du Québec à Trois-Rivières · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new Q555X mutation on the SYN1 gene was recently found in several members of a family segregating dyslexia, epilepsy, and autism spectrum disorder. To describe the effects of this mutation on cortical gray matter microstructure, we performed a surface-based group study using novel diffusion and quantitative multiparametric imaging on 13 SYN1

Indexed as

MutationAdolescentAdultAgedBrainCell Cycle ProteinsFamilyFemaleGray MatterHumansMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingPedigreeSynapsinsCell Cycle ProteinsSYN1 protein, humanSynapsinsadultautismcortexdyslexiaepilepsygeneticsMRI

Identifiers

PMID29671924
PMCPMC6866302
OpenAlexW2802608235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.