Evidence map›Paper›PMID 29671882›Full record

ArticleClinical cardiology2018

Electrocardiography scar quantification correlates with scar size of hypertrophic cardiomyopathy seen by multidetector computed tomography.

Tiago Costa Bignoto, Dalmo Antônio Ribeiro Moreira, Ricardo Garbe Habib, Edileide de Barros Correia, Ricardo Carneiro Amarante, Tannas Jatene, Mario Barbosa Guedes Nunes, Tiago Senra, Luiz Eduardo Mastrocolla

Open access · bronzeAbstract read
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Article in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tiago Costa BignotoInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9957-2516
Dalmo Antônio Ribeiro MoreiraInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Ricardo Garbe HabibInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Edileide de Barros CorreiaInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Ricardo Carneiro AmaranteInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Tannas JateneInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Mario Barbosa Guedes NunesInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Tiago SenraInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Luiz Eduardo MastrocollaInstitute of Cardiology Dante Pazzanese, São Paulo, Brazil.
Instituto Dante Pazzanese de Cardiologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertrophic cardiomyopathy (HCM), a genetically transmitted disease, is the most common genetic cardiovascular disease. Current strategies to stratify risk are expensive and concentrated in wealthy centers. Twelve-lead electrocardiography (ECG) is inexpensive, universally available, and can be readily used for Selvester QRS scoring, which estimates scar size. This study aimed to establish the relation between ECG scar quantification and myocardial fibrosis (extent of myocardial delayed enhancement) in multidetector computed tomography (MDCT). HYPOTHESIS: There is a significant association between ECG scar quantification and the extent of myocardial delayed enhancement in MDCT.

methodsSeventy-five patients with HCM underwent a routine clinical evaluation and echocardiography, 12-lead ECG, and MDCT study. Patients with and without an implantable cardioverter-defibrillator were included.

resultsThe estimated Selvester QRS score of myocardial fibrosis was correlated significantly (R = 0.70; P < 0.01) with the quantified MDCT fibrosis. Compared with MDCT, the QRS score had 84.8% sensitivity and 88.8% specificity. Myocardial fibrosis was present in 88% of these patients with HCM (fibrotic mass, 9.87 ±10.8 g) comprising 5.66% ±6.16% of the total myocardial mass seen on the MDCT images. The Selvester QRS score reliably predicted the fibrotic mass in 76% of patients, which estimated 8.44% ±7.39% of the total myocardial mass.

conclusionsThe Selvester QRS score provides reliable quantification of myocardial fibrosis and was well correlated with MDCT in patients with HCM.

Indexed as

ElectrocardiographyMultidetector Computed TomographyAdultCardiomyopathy, HypertrophicCicatrixFemaleFibrosisHumansMaleMiddle AgedMyocardiumObserver VariationPredictive Value of TestsPrognosisReproducibility of ResultsSeverity of Illness IndexHypertrophic CardiomyopathyMDCTMyocardial Delayed EnhancementMyocardial FibrosisSelvester QRS Score

Identifiers

PMID29671882
PMCPMC6489858
OpenAlexW2802778871

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.