Evidence map›Paper›PMID 29671217›Full record

ArticleNeuroscience bulletin2018

Cyproheptadine Regulates Pyramidal Neuron Excitability in Mouse Medial Prefrontal Cortex.

Yan-Lin He, Kai Wang, Qian-Ru Zhao, Yan-Ai Mei

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yan-Lin HeInstitutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, 200433, China. heyanlin@126.com.
Kai WangInstitutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, 200433, China.
Qian-Ru ZhaoInstitutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, 200433, China.
Yan-Ai MeiInstitutes of Brain Science, State Key Laboratory of Medical Neurobiology and School of Life Sciences, Fudan University, Shanghai, 200433, China. yamei@fudan.edu.cn.
State Key Laboratory of Medical NeurobiologyFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyproheptadine (CPH), a first-generation antihistamine, enhances the delayed rectifier outward K

Indexed as

AnimalsCyproheptadineFemaleHistamine H1 AntagonistsMembrane PotentialsMice, Inbred C57BLPatch-Clamp TechniquesPotassium Channel BlockersPotassium ChannelsPrefrontal CortexPyramidal CellsReceptors, sigmaTetraethylammoniumTissue Culture TechniquesCyproheptadineHistamine H1 AntagonistsPotassium Channel BlockersPotassium ChannelsReceptors, sigmaTetraethylammoniumcortical neuronsCyproheptadineNeuronal excitabilitySigma-1 receptorTetraethylammonium-sensitive I K

Identifiers

PMID29671217
PMCPMC6129243
OpenAlexW2800173881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.