Evidence map›Paper›PMID 29671110›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2018

Pulmonary cement embolism following cement-augmented fenestrated pedicle screw fixation in adult spinal deformity patients with severe osteoporosis (analysis of 2978 fenestrated screws).

Onur Levent Ulusoy, Sinan Kahraman, Isik Karalok, Emel Kaya, Meric Enercan, Cem Sever, Burak Abay, Selhan Karadereler, Azmi Hamzaoglu

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 51 citations in OpenAlex.

  1. Cement leakage risk reduction and propensity score matching analysis of clinical efficacy for Cement-Augmented fenestrated pedicle screw in patients with osteoporosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Pulmonary embolism and cement leakage in cement-augmented spinal instrumentation: incidence, associated factors, and clinical impact.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  10. [Postoperative ventricular tachycardia].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Onur Levent UlusoyDepartment of Radiology, Istanbul Florence Nightingale Hospital, Abide-i Hurriyet Cad. No:166 Sisli, 34381, Istanbul, Turkey. ulusoyolevent@gmail.com.ORCID 0000-0002-5482-166X
Sinan KahramanDepartment of Orthopaedics and Traumatology, Istanbul Bilim University Faculty of Medicine, Abide-i Hurriyet Cad. No:166 Sisli 34381, Istanbul, Turkey.
Isik KaralokDepartment of Radiology, Istanbul Bilim University Faculty of Medicine, Abide-i Hurriyet Cad. No:166 Sisli 34381, Istanbul, Turkey.
Emel KayaDepartment of Radiology, Istanbul Bilim University Faculty of Medicine, Abide-i Hurriyet Cad. No:166 Sisli 34381, Istanbul, Turkey.
Meric EnercanIstanbul Spine Center at Florence Nightingale Hospital, Abide-i Hurriyet Cad. No:160 Sisli, 34381, Istanbul, Turkey.
Cem SeverIstanbul Spine Center at Florence Nightingale Hospital, Abide-i Hurriyet Cad. No:160 Sisli, 34381, Istanbul, Turkey.
Burak AbayDepartment of Orthopaedics and Traumatology, Istanbul Bilim University Faculty of Medicine, Abide-i Hurriyet Cad. No:166 Sisli 34381, Istanbul, Turkey.
Selhan KaraderelerIstanbul Spine Center at Florence Nightingale Hospital, Abide-i Hurriyet Cad. No:160 Sisli, 34381, Istanbul, Turkey.
Azmi HamzaogluIstanbul Spine Center at Florence Nightingale Hospital, Abide-i Hurriyet Cad. No:160 Sisli, 34381, Istanbul, Turkey.
Istanbul Florence Nightingale Hospital · TRIstanbul Bilim University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is very limited information about pulmonary cement embolism (PCE) following cement-augmented fenestrated pedicle screw (CAFPS) fixation in the literature. The aim of this study to report the incidence of PCE following CAFPS fixation in adult deformity patients with severe osteoporosis and to identify risk factors such as; the number of levels, number of screws, and the cement volume used.

methods281 patients (204F, 77M) in whom CAFPS fixation was used during deformity surgery were included. All patients' routine postop 2 day chest X-rays and any available CT scans were reviewed by two radiologists. In patients with PCE, preop, early postop, and latest echocardiography studies were compared in terms of changes in pulmonary artery pressure (PAP) and right ventricular dilatation. Estimated cement volume used was calculated as: 2 cc (1 cc + 1 cc) per thoracic and 3 cc (1.5 cc + 1.5 cc) per lumbar levels, which are our routine protocol. Statistical analysis for risk factors was assessed with point biserial correlation test.

resultsAverage age is 70.5 (51-89) and average follow-up is 3.2 years (2-5). A total of 2978 CAFPS were instrumented with a mean of 10.5 levels (2-16) in 281 patients. PCE was diagnosed radiologically in 46 patients (16.3%). Among these 46 patients, PCE was clinically symptomatic in only 4 patients. Overall incidence of symptomatic PCE was 1.4% (4 of 281). Symptomatic PCE was statistically significant: when CAFPS fixation was performed > 7 levels; > 14 screws were used, and > 20-25 cc cement was used for augmentation (r = 0.378). In PCE group, mean preop PAP values of 27.40 (20-37) mm/Hg increased to 32.34 (20-50) mm/Hg in early postop and decreased to 28.29 (18-49) mm/Hg at final follow-up. In symptomatic PCE patients, mean preop PAP values of 30.75 (28-36) mm/Hg increased to 45.74 (40-50) mm/Hg in early postop and decreased to 38.75 (37-40) mm/Hg at final follow-up.

conclusionThis study showed an overall 16.3% radiological PCE and 1.4% symptomatic PCE incidence when CAFPS were used due to severe osteoporosis. The symptomatic PCE risk was significant when CAFPS were > 7 levels; > 14 fenestrated screws; and > 20-25 cc cement volume is used and this may cause PAP increase and right ventricular dilatation.

Indexed as

OsteoporosisSpinal DiseasesBone CementsEmbolismHumansLumbar VertebraePedicle ScrewsPostoperative ComplicationsSpinal FusionBone CementsFenestrated pedicle screwOsteoporotic spinePulmonary cement embolism

Identifiers

PMID29671110
OpenAlexW2800945375

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.