Evidence map›Paper›PMID 29671106›Full record

ArticleJournal of autism and developmental disorders2018

Autism Spectrum Symptomatology in Children with Williams Syndrome Who Have Phrase Speech or Fluent Language.

Bonita P Klein-Tasman, Faye van der Fluit, Carolyn B Mervis

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  7. Review
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  9. Translational Study of Copy Number Variations in Schizophrenia.International journal of molecular sciences · 2021
    Article
  10. Article
  11. Rhythm and timing as vulnerabilities in neurodevelopmental disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
  12. Williams syndrome.Nature reviews. Disease primers · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Bonita P Klein-TasmanDepartment of Psychology, University of Wisconsin-Milwaukee, P.O. Box 413, Milwaukee, WI, 53201, USA. bklein@uwm.edu.ORCID http://orcid.org/0000-0002-0932-1519
Faye van der FluitNorthwest Kaiser Permanente, 3550 N Interstate Avenue, Portland, OR, 97227, USA.
Carolyn B MervisDepartment of Psychological and Brain Sciences, University of Louisville, 317 Life Sciences Building, Louisville, KY, 40292, USA.
Kaiser Permanente · USUniversity of Louisville · USUniversity of Wisconsin–Milwaukee · US

Funding

GENOTYPE/PHENOTYPE CORRELATIONS IN WILLIAMS SYNDROMER01NS035102 · NINDS · UNIVERSITY OF LOUISVILLE · PI MERVIS, CAROLYN B. · 1996 to 2009
$12.5M
Early Development with Williams or Down SyndromeR37HD029957 · NICHD · UNIVERSITY OF LOUISVILLE · PI MERVIS, CAROLYN B. · 2004 to 2013
$3.4M
Social Behavior of Young Children with Williams SyndromeR03MH069400 · NIMH · UNIVERSITY OF WISCONSIN MILWAUKEE · PI KLEIN-TASMAN, BONITA P · 2004 to 2004
$68k
National Institute of Child Health and Human Development R37 HD29957National Institute of Mental Health R03 MH069400National Institute of Neurological Disorders and Stroke R01 NS35102NICHD NIH HHS R37 HD029957NIMH NIH HHS R03 MH069400NINDS NIH HHS R01 NS035102University of Wisconsin-Milwaukee Graduate School Research Committee AwardWilliams Syndrome Association 0104Williams Syndrome Association 0110Williams Syndrome Association 0111
6 · The paper itself

Abstract

To characterize autism spectrum-related symptomatology in children with Williams syndrome (WS) with phrase speech or fluent language, the Autism Diagnostic Observation Schedule Module 2 or 3 was administered. The cutoff for autism spectrum was met by 35% (14/40) who completed Module 2 and 30% (18/60) who completed Module 3. Similarities and differences in socio-communicative strengths and weaknesses as a function of language ability were identified. Symptom severity was negatively associated with IQ for participants with phrase speech but not for those with fluent language. The findings suggest an elevated risk of ASD for individuals with WS relative to the general population and contribute to a more nuanced sense of the socio-communicative functioning of children with WS.

Indexed as

LanguageAdolescentAutism Spectrum DisorderChildChild, PreschoolCommunicationFemaleHumansMaleSpeechWilliams SyndromeAutism spectrum disordersIntellectual disabilitySocial communicationWilliams syndrome

Identifiers

PMID29671106
PMCPMC6082683
OpenAlexW2800570473

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.