ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2018
Agreement and repeatability of objective systems for assessment of the tear film.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Okra eyelid patch versus sodium hyaluronate combined with ofloxacin eye drop in the treatment of meibomian gland dysfunction: a randomized controlled trial.BMC ophthalmology · 2026Trial
- Comparing automated and manual assessments of tear break-up time using different non-invasive devices and a fluorescein procedure.Scientific reports · 2024Trial
- Effect of a single warm compress prior to ophthalmic surgery on ocular surface and intraoperative visibility: a randomised controlled study.BMJ open ophthalmology · 2023Trial
- Comparative analysis of subjective and objective visual quality after LASEK, FS-LASIK, and TransPRK.Lasers in medical science · 2026Article
- Dynamic Tear Film Stability Assessed via an Open-View Double-Pass Imaging System.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- How ptosis affects the visual quality: an overview of visual quality impairments and contributing factors in ptotic eyes.International ophthalmology · 2025Review
- Agreement between invasive and noninvasive measurement of tear film breakup time.Scientific reports · 2024Article
- Screening of positive dysphotopsia before multifocal intraocular lens implantation.Indian journal of ophthalmology · 2024Article
- Face Mask and Tear Film Stability: A Pilot Study of the Objective Measurement of Tear Break-Up Time.Journal of clinical medicine · 2023Article
- Repeatability, reproducibility and agreement between three different diagnostic imaging platforms for tear film evaluation of normal and dry eye disease.Eye (London, England) · 2023Article
- Lacrimal and meibomian gland evaluation in dry eye disease: A mini-review.Indian journal of ophthalmology · 2023Review
- Altered Ocular Surface Health Status and Tear Film Immune Profile Due to Prolonged Daily Mask Wear in Health Care Workers.Biomedicines · 2022Article
- Topographic tear film trend and new parameters for non-invasive break up time test.International journal of ophthalmology · 2022Article
- Repeatability of Non-invasive Keratograph Break-Up Time measurements obtained using Oculus Keratograph 5M.International ophthalmology · 2021Article
- The Association between Tear Film Thickness as Measured with OCT and Symptoms and Signs of Dry Eye Disease: A Pooled Analysis of 6 Clinical Trials.Journal of clinical medicine · 2020Article
- Repeatability of non-invasive break-up time measures with a new automated dry eye platform in healthy eyes.International ophthalmology · 2020Article
- Optical quality in low astigmatic eyes with or without cylindrical correction.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Tear Film Characteristics During Wear of Daily Disposable Contact Lenses.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Objective assessment of optical quality in dry eye disease using a double-pass imaging system.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Effects of Blink Rate on Tear Film Optical Quality Dynamics with Different Soft Contact Lenses.Journal of ophthalmology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeTo assess the agreement and repeatability of two objective systems for measuring the tear film stability.
methodsRetrospective analysis of the tear film stability of 99 healthy right eyes measured with a videokeratoscope (VK) and the Optical Quality Analysis System (OQAS, Visiometrics). Two consecutive measures were taken with both systems, with an interval of 10 min between them. Variables included in the study were first and mean non-invasive break-up times (NIBUT and MNIBUT) measured with VK, and mean and standard deviation of the optical scattering index (OSIm and OSIsd) measured with OQAS. The agreement and repeatability of grading scales provided by both devices were also evaluated using the Cohen's k with quadratic weights. The Ocular Surface Disease index (OSDI) questionnaire was also passed out to all subjects. Correlations and associations between subjective and objective metrics were analyzed.
resultsSignificant differences were found between consecutive measurements of NIBUT (p = 0.04) and MNIBUT (p = 0.01), but not for OSIm (p = 0.11) and OSIsd (p = 0.50). Grading scales resulted in fair (k = 0.20) or poor agreement (k = 0.04) between systems depending if the first or second trial was considered. The repeatability of the grading scale was good for OQAS (k = 0.59) and fair for VK (k = 0.37). No significant correlations or associations were found between OSDI and any of the metrics obtained with both devices (p ≥ 0.36).
conclusionsThe two devices evaluated cannot be used interchangeably for the assessment of tear film stability. Good intrasession repeatability was obtained for tear film grading of the OQAS whereas it was fair for VK.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.