Evidence map›Paper›PMID 29671052›Full record

ArticlePsychological research2019

Is it possible to modify fear memories in humans with extinction training within a single day?

Jaime Redondo, Jose Fernandez-Rey, Daniel Gonzalez-Gonzalez

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In one paragraph

Article in Psychological research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jaime RedondoCognitive Processes and Behavior Lab, Faculty of Psychology, University of Santiago de Compostela,, Santiago, Spain. j.redondo@usc.es.
Jose Fernandez-ReyCognitive Processes and Behavior Lab, Faculty of Psychology, University of Santiago de Compostela,, Santiago, Spain.
Daniel Gonzalez-GonzalezCognitive Processes and Behavior Lab, Faculty of Psychology, University of Santiago de Compostela,, Santiago, Spain.

Funding

Xunta de Galicia GRC 2015/006
6 · The paper itself

Abstract

Extinction procedures have been used widely in the study of fear memories, and different positions have been adopted regarding the efficacy of such procedures and the mechanisms involved. It has been argued that extinction may interfere with the consolidation of the fear memory if the procedure is applied with the appropriate timing after acquisition. However, the opposite position is also held, that is, that the extinction does not achieve an elimination of the fear response. The aim of the present study is to test the short-term effects of immediate extinction in fear reduction when this extinction is preceded by a retrieval trial. For this, a procedure similar to that employed by Schiller et al. (Nature 463(7277): 49-53, 2010) was used, but in a single day and with white noise as an aversive unconditioned stimulus. The results indicate that a CS+ single retrieval trial before the extinction procedure after acquisition was more effective in fear reduction than standard immediate extinction.

Indexed as

Extinction, PsychologicalFearMemoryConditioning, ClassicalFemaleHumansMaleYoung Adult

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.