Evidence map›Paper›PMID 29671001›Full record

ArticleClinical neuroradiology2019

Cervical Spine Prospective Feasibility Study : Dynamic Flexion-Extension Diffusion-Tensor Weighted Magnetic Resonance Imaging.

Bawarjan Schatlo, Luca Remonda, Philipp Gruber, Javier Fandino, Veit Rohde, Ali-Reza Fathi, Jatta Berberat

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Article in Clinical neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bawarjan SchatloDepartment of Neuroradiology, Cantonal Hospital Aarau, Tellstraße 25, 5001, Aarau, Switzerland.
Luca RemondaDepartment of Neuroradiology, Cantonal Hospital Aarau, Tellstraße 25, 5001, Aarau, Switzerland.
Philipp GruberDepartment of Neurology, Cantonal Hospital Aarau, Aarau, Switzerland.
Javier FandinoDepartment of Neurosurgery, Cantonal Hospital Aarau, Aarau, Switzerland.
Veit RohdeDepartment of Neurosurgery, University Medicine Göttingen, Georg-August University, Göttingen, Germany.
Ali-Reza FathiDepartment of Neurosurgery, Hirslanden Clinik, Aarau, Switzerland.
Jatta BerberatDepartment of Neuroradiology, Cantonal Hospital Aarau, Tellstraße 25, 5001, Aarau, Switzerland. jatta.berberat@ksa.ch.ORCID http://orcid.org/0000-0002-6551-8308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiffusion tensor imaging (DTI) in flexion-extension may serve as a diagnostic tool to improve the sensitivity for detection of myelopathy. In this study, the feasibility and reproducibility of dynamic DTI in the cervical spinal cord was assessed in healthy volunteers and patients.

methodsAll subjects were examined in maximum neck flexion-extension in a 3T magnetic resonance imaging (MRI) scanner. Range of motion, space available for the spinal cord, fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured and compared between the neck positions.

resultsVolunteers showed no variation in ADC and FA. In patients, extension produced higher ADC in the diseased than in the control segments (p = 0.0045). The ADC of the affected segments was higher in extension than in the neutral position (p = 0.0030) or in flexion (p = 0.0002). The FA was significantly lower in extension in patients at both the control level C2/3 (p = 0.0154) and the affected segment (p = 0.0187).

conclusionsDynamic DTI of the cervical spine is feasible and ADC increased in the patient group in extension. This finding may open a previously unexplored avenue to attempt an earlier identification of myelopathy.

Indexed as

AdultAnisotropyCase-Control StudiesCervical VertebraeDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingFeasibility StudiesFemaleHealthy VolunteersHumansMaleMiddle AgedObserver VariationPatient PositioningPostureProspective StudiesCervical myelopathyDiffusion tensor imagingDynamic magnetic resonance imagingExtensionFlexion

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.