Evidence map›Paper›PMID 29670927›Full record

ArticleOpen forum infectious diseases2017

Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection.

William A Fischer, Jerry Brown, David Alain Wohl, Amy James Loftis, Sam Tozay, Edwina Reeves, Korto Pewu, Galapaki Gorvego, Saturday Quellie, Coleen K Cunningham and 7 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Use of Ebola Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Can Marburg virus be sexually transmitted?Health science reports · 2024
    Article
  9. Atypical Ebola Virus Disease in a Rhesus Macaque.The Journal of infectious diseases · 2023
    Article
  10. Article
  11. Article
  12. The role of immune activation and antigen persistence in acute and long COVID.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2023
    Review
  13. Article
  14. Post-Ebola Symptoms 7 Years After Infection: The Natural History of Long Ebola.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  15. Risk Factors for Ebola Virus Persistence in Semen of Survivors in Liberia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

William A FischerDivisions of Pulmonary and Critical Care Medicine and.
Jerry BrownEternal Love Winning Africa Hospital, Monrovia, Liberia.
David Alain WohlInfectious Disease and.
Amy James LoftisInfectious Disease and.
Sam TozayEternal Love Winning Africa Hospital, Monrovia, Liberia.
Edwina ReevesEternal Love Winning Africa Hospital, Monrovia, Liberia.
Korto PewuEternal Love Winning Africa Hospital, Monrovia, Liberia.
Galapaki GorvegoEternal Love Winning Africa Hospital, Monrovia, Liberia.
Saturday QuelliePhebe Hospital & School of Nursing, Suakoko, Bong County, Liberia.
Coleen K CunninghamDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Carson MerenbloomInfectious Disease and.
Sonia NapravnikInfectious Disease and.
Karine DubePublic Health Leadership Program, The University of North Carolina at Chapel Hill.
David AdjasooClinical Research Management, Inc. (ClinicalRM), Hinckley, Ohio; and.
Erin JonesClinical Research Management, Inc. (ClinicalRM), Hinckley, Ohio; and.
Korlia BonarwoloEbola Survivor Association of Liberia Inc, Monrovia.
David HooverClinical Research Management, Inc. (ClinicalRM), Hinckley, Ohio; and.
University of Liberia · LRInfectious Disease Consultants · USClinical Research Management · USDuke Medical Center · USLiberian Institute for Biomedical Research · LRPlanned Parenthood Association of Liberia · LRPulmonary and Critical Care Associates · USUniversity of North Carolina at Chapel Hill · US

Funding

Clinical Sequelae and Urogenital Viral Dynamics in Survivors of Ebola Virus DiseaseR01AI123535 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FISCHER, WILLIAM, WOHL, DAVID A · 2017 to 2021
$3.3M
Mentoring New Investigators in Criminal Justice HIV Prevention and TreatmentK24DA037101 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOHL, DAVID A · 2014 to 2018
$911k
Clinical Sequelae and Urogenital Viral Dynamics in Survivors of Ebola Virus DiseaseK23AI121516 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FISCHER, WILLIAM · 2016 to 2019
$783k
NIAID NIH HHS K23 AI121516NIAID NIH HHS R01 AI123535NIDA NIH HHS K24 DA037101
6 · The paper itself

Abstract

Among 149 men who survived Ebola virus disease (EVD) and donated semen 260-1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.

Indexed as

EbolaPCRsemenviral persistence

Identifiers

PMID29670927
PMCPMC5897835
OpenAlexW2738420978

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.