Evidence map›Paper›PMID 29670918›Full record

ArticleJournal of immunology research2018

Management of Patients with Graves' Disease and Orbital Involvement: Role of Spectral Domain Optical Coherence Tomography.

Alice Bruscolini, Maurizio La Cava, Magda Gharbiya, Marta Sacchetti, Lucia Restivo, Chiara Nardella, Marco Marenco, Alessandro Lambiase

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alice BruscoliniDepartment of Sense Organs, University Sapienza, Rome, Italy.ORCID 0000-0002-1627-5493
Maurizio La CavaDepartment of Sense Organs, University Sapienza, Rome, Italy.
Magda GharbiyaDepartment of Sense Organs, University Sapienza, Rome, Italy.
Marta SacchettiDepartment of Sense Organs, University Sapienza, Rome, Italy.
Lucia RestivoDepartment of Sense Organs, University Sapienza, Rome, Italy.
Chiara NardellaDepartment of Sense Organs, University Sapienza, Rome, Italy.
Marco MarencoDepartment of Sense Organs, University Sapienza, Rome, Italy.ORCID 0000-0002-3755-4352
Alessandro LambiaseDepartment of Sense Organs, University Sapienza, Rome, Italy.ORCID 0000-0002-8974-991X
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the role of choroidal thickness evaluation with spectral domain optical coherence tomography (SDOCT) and enhanced depth imaging (EDI) technique in the management of patients with Graves' disease and orbitopathy (GO).

methodsThirty-six eyes of 18 patients with GO and 36 eyes of 18 age-matched control subjects were included in this retrospective observational study. All the subjects underwent a complete ophthalmological evaluation, including clinical activity score (CAS) and exophthalmometry. The SDOCT images of the choroid were obtained by EDI modality.

resultsChoroidal thickness was significantly increased in GO than in control eyes (

conclusionThis study shows that choroidal thickness, evaluated with EDI-OCT, is significantly increased in patients with GO and correlates with the activity of the disease, proptosis, and duration of the disease. The choroidal thickening may reflect the ocular hemodynamic changes, and enhanced depth imaging optical coherence tomography may be a useful tool for the evaluation of orbital congestion and management of patients with Graves' disease and orbital involvement.

Indexed as

AdultChoroidDisease ProgressionExophthalmosFemaleGraves DiseaseHemodynamicsHumansMaleMiddle AgedOrbitRetrospective StudiesTomography, Optical CoherenceYoung Adult

Identifiers

PMID29670918
PMCPMC5835242
OpenAlexW2788637885

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.