ArticleFrontiers in pediatrics2018
Pathogenetic and Prognostic Factors for Neonatal Gastric Perforation: Personal Experience and Systematic Review of the Literature.
Article in Frontiers in pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- Spontaneous gastric perforation in a term neonate: a case report and literature review.International journal of surgery case reports · 2026Article
- Neonatal Gastric Perforation Temporally Associated with Nasogastric Tube Insertion: A Case Report.International medical case reports journal · 2026Article
- Neonatal total gastrectomy as treatment for gastric rupture: Case report.International journal of surgery case reports · 2025Article
- Effect of early postoperative enteral nutrition on the short-term prognosis in neonatal gastric perforation.Pediatric discovery · 2025Article
- Identifying Preoperative Clinical Characteristics of Unexpected Gastrointestinal Perforation in Infants-A Retrospective Cohort Study.Children (Basel, Switzerland) · 2024Article
- Article
- Spontaneous gastric perforation complicating acute laryngotracheobronchitis in an infant: a novel case report from Nepal.Journal of surgical case reports · 2023Article
- Case report: Catastrophic event: neonatal gastric perforation and complication of capillary leak syndrome.Frontiers in pediatrics · 2023Article
- Sleeve gastrectomy for multiple gastric perforations in a preterm: A case report.Clinical case reports · 2022Article
- Neonatal Gastric Necrosis and Perforation Treated by Subtotal Gastrectomy and Esogastric Anastomosis: A Case Report.The American journal of case reports · 2021Article
- Development and Validation of a Nomogram for Preoperative Prediction of Localization of Neonatal Gastrointestinal Perforation.Frontiers in pediatrics · 2021Article
- Risk Factors for Mortality in Neonatal Gastric Perforation: A Retrospective Cohort Study.Frontiers in pediatrics · 2021Article
- Total gastrectomy with delayed Hunt-Lawrence pouch reconstruction for neonatal gastric perforation presenting with hematemesis.Journal of pediatric surgery case reports · 2020Article
- Gastric perforation resulting into pneumoperitoneum in a neonate: a case report.Journal of surgical case reports · 2020Article
- Recurrent intestinal ischemia following surgery for gastric and duodenal perforations: a case report.Surgical case reports · 2019Article
- [Spontaneous gastric perforation complicating spontaneous acute bronchiolitis in an infant].The Pan African medical journal · 2019Article
- Neonatal Gastric Perforation: Our Experience and Important Preoperative and Intraoperative Caveats to Prognosticate and Improve Survival.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNeonatal gastric perforation (NGP) is a rare entity. Our aim was to report our experience and review the recent literature to characterize NGP, describe associated factors, and define prognostic factors. MATERIALS AND
methodsRetrospective review of all consecutive patients with NGP treated between June 2009 and December 2017 in a third level pediatric hospital. In addition, a systematic review of Medline and Scopus database was performed using a defined strategy. All articles referring to NGP published between 2005 and 2017 were retrieved. Variables considered: prematurity (<37 weeks gestation), birth weight (BW), Apgar score, prenatal complications, age at diagnosis, bag ventilation, pathogenetic events, site of perforation, treatment of perforation, sepsis, and outcome. Mann-Whitney or Fisher's test were used as appropriate. Results are median (range) or prevalence.
resultsBetween 2009 and 2016 we treated 8 consecutive patients for NGP and 199 further cases were retrieved from the systematic review (total of 207 patients). Overall survival was 73%. Most frequently reported pathogenesis: iatrogenic (20 patients), hypoxic/ischemic or infection stress (13 patients), duodenal/jejunal obstruction (11 patients), drugs (11 patients), esophageal atresia (10 patients). 60% patients had only primary repair of the perforation as gastric surgery. Sepsis developed in 56 patients (34%).
conclusionAlthough the pathogenesis of NGP is pleomorphic, prematurity and low BWs are frequent in these patients. Reviewing our experience and the available literature, none of the variables considered, but sepsis was associated with mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.