ArticleTranslational vision science & technology2018
Improved High-Frequency Ultrasound Corneal Biometric Accuracy by Micrometer-Resolution Acoustic-Property Maps of the Cornea.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Enhancing 3-D Radio Frequency Data in Quantitative Acoustic Microscopy Using Quantum-Driven Prior at 250 MHz and 500 MHz.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- A Quantum Denoising-Based Resolution Enhancement Framework for 250-MHz and 500-MHz Quantitative Acoustic Microscopy.IEEE transactions on computational imaging · 2024Article
- Advanced Topics in Quantitative Acoustic Microscopy.Advances in experimental medicine and biology · 2023Article
- Biomechanics of Ophthalmic Crosslinking.Translational vision science & technology · 2021Review
- Regional changes in the elastic properties of myopic Guinea pig sclera.Experimental eye research · 2019Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeMapping of epithelial thickness (ET) is useful for detection of keratoconus, a disease characterized by corneal thinning and bulging in which epithelial thinning occurs over the apex. In prior clinical studies, optical coherence tomography (OCT) measurements of ET were systematically thinner than those obtained by 40-MHz high-frequency ultrasound (HFU) where a constant speed of sound (
methodsTwelve unfixed pig corneas were snap-frozen and 6-μm sections were scanned using a custom-built SAM with an F-1.08, 500-MHz transducer and a 264-MHz bandwidth. Two-dimensional maps of
resultsSAM showed that the value of
conclusionSAM results demonstrated that the assumption of a constant value of TRANSLATIONAL RELEVANCE: The findings of this study have important implications for HFU-based ET measurements and will improve future keratoconus diagnosis by providing more-accurate ET estimates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.