Evidence map›Paper›PMID 29670789›Full record

ArticleCase reports in ophthalmological medicine2018

Repeat Intravitreal Dexamethasone Implant for Refractory Cystoid Macular Edema in Syphilitic Uveitis.

Cassandra C Lautredou, Joshua S Hardin, John R Chancellor, Sami H Uwaydat, Abdallah A Ellabban, Ahmed B Sallam

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmological medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Cassandra C LautredouCollege of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Joshua S HardinJones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
John R ChancellorJones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Sami H UwaydatJones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Abdallah A EllabbanDepartment of Ophthalmology, Suez Canal University, Ismailia, Egypt.
Ahmed B SallamJones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID 0000-0001-7207-6782
University of Arkansas for Medical Sciences · USSuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the successful utilization of adjunctive repeat intravitreal corticosteroid therapy for the treatment of cystoid macular edema in syphilis-related uveitis. METHODS/PATIENTS: An HIV-positive patient with treated ocular syphilis who developed refractory cystoid macular edema (CME) was treated with repeat intravitreal corticosteroid therapy including dexamethasone intravitreal implants.

resultsTreatment led to the resolution of CME and improvement in visual acuity.

conclusionsIntravitreal corticosteroid therapy may be a viable adjunctive treatment for refractory CME in patients with treated syphilitic uveitis. Corticosteroid-induced exacerbation of infection is unlikely in patients with an adequate serologic treatment response.

Identifiers

PMID29670789
PMCPMC5836310
OpenAlexW2793553281

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.