Evidence map›Paper›PMID 29670753›Full record

ArticleObesity science & practice2018

Association of changes in mental health with weight loss during intensive lifestyle intervention: does the timing matter?

N Alhalel, S M Schueller, M J O'Brien

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. The impact of adult behavioural weight management interventions on mental health: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

N AlhalelNorthwestern University Feinberg School of Medicine Chicago IL USA.
S M SchuellerDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL USA.
M J O'BrienDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL USA.ORCID 0000-0001-8882-9865
Northwestern University · US

Funding

Promotora-Led Intervention to Promote Weight Loss in Latinas at-risk for DiabetesK23DK095981 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI O'BRIEN, MATTHEW JAMES · 2012 to 2016
$890k
Connecting Patients and Therapists Using a Tech-Based Treatment Support SystemK08MH102336 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHUELLER, STEPHEN · 2014 to 2017
$678k
Promotora Intervention for Metabolic and MentalHealth (PRIME2)R03DK109243 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI O'BRIEN, MATTHEW JAMES · 2017 to 2018
$163k
NIDDK NIH HHS K23 DK095981NIDDK NIH HHS R03 DK109243NIMH NIH HHS K08 MH102336
6 · The paper itself

Abstract

Objective: This study examined changes in mental health symptoms and weight during weight loss treatment. It was hypothesized that worsening mental health would negatively impact weight loss. Methods: Data were analyzed from a trial of 92 Hispanic women with overweight/obesity and prediabetes, who were randomized to receive intensive lifestyle intervention (ILI), metformin 1,700 mg daily, or standard care. Depression, anxiety and perceived stress were assessed at 0, 6 and 12 months. Six- and 12-month weight change was compared among participants whose symptom scores worsened on any mental health measure (W) vs. improved or remained stable on all three (I/S). Results: Among ILI participants, the 12-month difference in weight loss between I/S and W groups was statistically significant: -5.1 kg (P = 0.001). From baseline to 6 months, ILI participants in I/S and W groups experienced comparable weight loss. However, from 6 to 12 months, W participants regained weight, whereas I/S participants experienced continued weight loss. In the metformin and standard care arms, there was no weight difference between I/S and W groups. Conclusions: In ILI, 12-month improvement or stability in mental health was significantly associated with weight loss. Weight trajectories between I/S and W groups diverged at 6 months.

Indexed as

Anxietydepressionperceived stressweight loss

Identifiers

PMID29670753
PMCPMC5893461
OpenAlexW2793547856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.