Evidence map›Paper›PMID 29670727›Full record

ArticleJournal of clinical and experimental dentistry2018

Estimation of salivary cortisol among subjects undergoing dental extraction.

Srikanth Gadicherla, Revathi-Panduranga Shenoy, Bhavik Patel, Meenakshi Ray, Brijesh Naik, Kalyana-Chakravarthy Pentapati

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04110379 (Effect of Virtual Reality Glasses as a Distraction Method on Child's Anxiety During Dental Treatment), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04110379 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Virtual Reality Glasses as a Distraction Method on Child's Anxiety During Dental Treatment(Randomized Controlled Clinical Trial)

TypeinterventionalSponsorNourhan M.AlyRan2019 to 2020Enrolled40ConditionsDental AnxietyArmsVirtual Reality (VR), Conventional Behavior Management Techniques
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  7. Treatment and Prevention of Adrenal Crisis and Family EducationJournal of clinical research in pediatric endocrinology · 2025
    Review
  8. Salivary Cortisol as a Stress Monitor During Third Molar Surgery.Journal of maxillofacial and oral surgery · 2022
    Article
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Srikanth GadicherlaDepartment of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal.
Revathi-Panduranga ShenoyDepartment of Biochemistry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal.
Bhavik PatelDepartment of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal.
Meenakshi RayDepartment of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal.
Brijesh NaikDepartment of Biochemistry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal.
Kalyana-Chakravarthy PentapatiDeparment of Public Health Dentistry, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDental procedures can be stressful and studies have shown that salivary cortisol is elevated during such procedures. Our study aimed to evaluate saliva cortisol levels among the subjects who underwent dental extractions and to compare it with that of the controls. The secondary objective of the study was to evaluate any correlation between salivary cortisol and hemodynamic parameters. MATERIAL AND

methodsWe conducted this clinical study among subjects, who were indicated for dental extraction. Saliva samples from the subjects in the study group were collected before and after (10 mins) the dental extraction. Hemodynamic parameters like heart rate, systolic (SBP) and diastolic blood pressure (DBP) and oxygen saturation (Sp O2) were measured 10 minutes prior to the dental extraction and after completion of the extraction by a single trained examiner. Salivary cortisol was estimated by solid phase enzyme-linked immunosorbent assay (ELISA).

resultsA total of 31 subjects in the study group and 24 subjects in control group have participated in this study. The mean salivary cortisol concentration was significantly higher after extraction (27.94±7.94) than before extraction (24.67±8.31) in the study group (

conclusionsDental extractions and local anaesthetic procedures can induce stress in subjects. Dental care providers should try to minimise the subject's anxiety and stress to the maximum extent.

Identifiers

PMID29670727
PMCPMC5899797

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.