Evidence map›Paper›PMID 29670697›Full record

ArticleACS medicinal chemistry letters2018

Imidazo[2,1-

Michael S Christodoulou, Federico Dapiaggi, Francesca Ghiringhelli, Stefano Pieraccini, Maurizio Sironi, Marianna Lucafò, Debora Curci, Giuliana Decorti, Gabriele Stocco, Chandra Sekhar Chirumamilla and 7 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Michael S ChristodoulouDISFARM, Sezione di Chimica Generale e Organica "A. Marchesini", Università degli Studi di Milano, Via Venezian 21, 20133 Milano, Italy.
Federico DapiaggiDepartment of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milano Italy.
Francesca GhiringhelliDepartment of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milano Italy.
Stefano PieracciniDepartment of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milano Italy.
Maurizio SironiDepartment of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milano Italy.
Marianna LucafòDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Debora CurciPhD School in Reproduction and Developmental Sciences, University of Trieste, 34127 Trieste, Italy.
Giuliana DecortiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Gabriele StoccoDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Chandra Sekhar ChirumamillaLaboratory of Protein Chemistry, Proteomics and Epigenetic Signalling, Department of Biomedical Sciences, University of Antwerp (UA), 2000 Antwerpen, Belgium.
Wim Vanden BergheLaboratory of Protein Chemistry, Proteomics and Epigenetic Signalling, Department of Biomedical Sciences, University of Antwerp (UA), 2000 Antwerpen, Belgium.
Patrick BalaguerIRCM, INSERM U1194, Université Montpellier, ICM, 208 rue des Apothicaires, F-34298 Montpellier, France.
Benoît Y MichelUniversité Côte d'Azur, CNRS, Institut de Chimie de Nice, UMR 7272, Parc Valrose, 06108 Nice Cedex 2, France.
Alain BurgerUniversité Côte d'Azur, CNRS, Institut de Chimie de Nice, UMR 7272, Parc Valrose, 06108 Nice Cedex 2, France.
Egle M BeccalliDISFARM, Sezione di Chimica Generale e Organica "A. Marchesini", Università degli Studi di Milano, Via Venezian 21, 20133 Milano, Italy.
Daniele PassarellaDepartment of Chemistry, Università degli Studi di Milano, Via Golgi 19, 20133 Milano Italy.
Nadine MartinetUniversité Côte d'Azur, CNRS, Institut de Chimie de Nice, UMR 7272, Parc Valrose, 06108 Nice Cedex 2, France.
University of Milan · ITUniversity of Trieste · ITCentre National de la Recherche Scientifique · FRUniversity of Antwerp · BEInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucocorticoid receptor (GCR) transactivation reporter gene assays were used as an initial high-throughput screening on a diversified library of 1200 compounds for their evaluation as GCR antagonists. A class of imidazo[2,1-

Identifiers

PMID29670697
PMCPMC5900336
OpenAlexW2789205394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.