Evidence map›Paper›PMID 29670668›Full record

ArticleDisease markers2018

Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (

Agata Sakowicz, Michalina Lisowska, Lidia Biesiada, Magda Rybak-Krzyszkowska, Agnieszka Gach, Bartosz Sakowicz, Mariusz Grzesiak, Hubert Huras, Tadeusz Pietrucha

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  9. [Vitamin D down-regulates microRNA-21 expression to promote human placental trophoblast cell migration and invasionNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Agata SakowiczDepartment of Medical Biotechnology, Medical University of Lodz, Łódź, Poland.ORCID 0000-0002-5083-2046
Michalina LisowskaDepartment of Medical Biotechnology, Medical University of Lodz, Łódź, Poland.
Lidia BiesiadaDepartment of Obstetrics, Perinatology and Gynecology, Polish Mother's Memorial Hospital Research Institute, Łódź, Poland.
Magda Rybak-KrzyszkowskaDepartment of Obstetrics and Perinatology, University Hospital in Kraków, Kraków, Poland.
Agnieszka GachDepartment of Genetics, Polish Mother's Memorial Hospital-Research Institute, Łódź, Poland.
Bartosz SakowiczDepartment of Microelectronics and Computer Science, Lodz University of Technology, Łódź, Poland.
Mariusz GrzesiakDepartment of Obstetrics, Perinatology and Gynecology, Polish Mother's Memorial Hospital Research Institute, Łódź, Poland.
Hubert HurasDepartment of Obstetrics and Perinatology, University Hospital in Kraków, Kraków, Poland.
Tadeusz PietruchaDepartment of Medical Biotechnology, Medical University of Lodz, Łódź, Poland.
Medical University of Lodz · PLPolish Mother’s Memorial Hospital Research Institute · PLKrakow Cardiovascular Research Institute · PLLodz University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetalloproteinases (MMPs) play a pivotal role during the process of trophoblast invasion and placentation. The appearance of five functional single-nucleotide polymorphisms (SNP) in the genes of the metalloproteinases most commonly implicated in the implantation process may influence the development of preeclampsia.

methodsBlood samples were collected from 86 mothers and 86 children after preeclampsia and 85 mothers and 85 children with uncomplicated pregnancies. The distribution of genotypes for -1607 1G/2G

resultsThe occurrence of 1G/1G

conclusionThe maternal 1G/1G

Indexed as

Polymorphism, Single NucleotideAdultCase-Control StudiesFemaleHumansInfant, NewbornMaleMatrix MetalloproteinasesPre-EclampsiaPregnancyMatrix Metalloproteinases

Identifiers

PMID29670668
PMCPMC5835279
OpenAlexW2791832520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.