Evidence map›Paper›PMID 29670621›Full record

ArticleFrontiers in immunology2018

Integrated Analysis Reveals That miR-193b, miR-671, and TREM-1 Correlate With a Good Response to Treatment of Human Localized Cutaneous Leishmaniasis Caused by

Sara Nunes, Icaro Bonyek Silva, Mariana Rosa Ampuero, Almério Libório Lopes de Noronha, Lígia Correia Lima de Souza, Thaizza Cavalcante Correia, Ricardo Khouri, Viviane Sampaio Boaventura, Aldina Barral, Pablo Ivan Pereira Ramos and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. A review on the role of miR-671 in human disorders.Frontiers in molecular biosciences · 2022
    Review
  8. Review
  9. Review
  10. Pathogens (Basel, Switzerland) · 2021
    Article
  11. Review
  12. miR-548d-3p Alters Parasite Growth and Inflammation inFrontiers in cellular and infection microbiology · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Frontiers in immunology · 2019
    Review
  17. Article
  18. Expression of Mir-21 and Mir-103a inIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Sara NunesOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Icaro Bonyek SilvaOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Mariana Rosa AmpueroOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Almério Libório Lopes de NoronhaLaboratório de Anatomia Patológica, Feira de Santana, Brazil.
Lígia Correia Lima de SouzaFederal University of Bahia, Salvador, Brazil.
Thaizza Cavalcante CorreiaOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Ricardo KhouriOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Viviane Sampaio BoaventuraOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Aldina BarralOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Pablo Ivan Pereira RamosOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Cláudia BrodskynOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Pablo Rafael Silveira OliveiraFederal University of Bahia, Salvador, Brazil.
Natalia Machado TavaresOswaldo Cruz Foundation, Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil.
Fundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BRUniversidade Estadual de Feira de Santana · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Localized cutaneous leishmaniasis (LCL) is a chronic disease characterized by ulcerated skin lesion(s) and uncontrolled inflammation. The mechanisms underlying the pathogenesis of LCL are not completely understood, and little is known about posttranscriptional regulation during LCL. MicroRNAs (miRNAs) are non-coding small RNAs that regulate gene expression and can be implicated in the pathogenesis of LCL. We investigated the involvement of miRNAs and their targets genes in human LCL using publicly available transcriptome data sets followed by

Indexed as

Biomarkers, PharmacologicalCD40 AntigensGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksHumansLeishmania braziliensisLeishmaniasis, CutaneousMicroRNAsReceptors, Tumor Necrosis Factor, Type ISkin Physiological PhenomenaTreatment OutcomeTriggering Receptor Expressed on Myeloid Cells-1Wound HealingBiomarkers, PharmacologicalCD40 AntigensMicroRNAsMIRN193 microRNA, humanMIRN671 microRNA, humanReceptors, Tumor Necrosis Factor, Type ITriggering Receptor Expressed on Myeloid Cells-1human leishmaniasisLeishmania braziliensismicroRNAskintranscriptomeTREM-1

Identifiers

PMID29670621
PMCPMC5893808
OpenAlexW2795657712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.