Evidence map›Paper›PMID 29670614›Full record

ArticleFrontiers in immunology2018

Human Vγ9Vδ2-T Cells Synergize CD4

Qingyun Chen, Kun Wen, Aizhen Lv, Ming Liu, Ke Ni, Zheng Xiang, Yinping Liu, Wenwei Tu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Generation of CCR4/CD7 Bispecific CAR-T Cells Resistant to Fratricide and Exhaustion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Increase of Vδ2Immune network · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Qingyun ChenDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Kun WenDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Aizhen LvDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Ming LiuState Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.
Ke NiDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Zheng XiangDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Yinping LiuDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Wenwei TuDepartment of Paediatrics and Adolescent Medicine, University of Hong Kong, Pokfulam, Hong Kong.
Queen Mary Hospital · CNUniversity of Hong Kong · HKState Key Laboratory of Respiratory Disease · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Vγ9Vδ2-T cells recognize nonpeptidic antigens and exert effector functions against microorganisms and tumors, but little is known about their roles in humoral immune response against influenza virus infection. Herein, in the coculture of autologous human B cells, dendritic cells and/or naïve CD4 T cells, and Vγ9Vδ2-T cells, we demonstrated that Vγ9Vδ2-T cells could facilitate H9N2 influenza virus-specific IgG and IgM productions in a CD4 T cell-dependent manner. Vγ9Vδ2-T cells promoted the differentiation of CXCR5

Indexed as

AnimalsAntibodies, ViralAntibody SpecificityCell DifferentiationCytokinesEnzyme-Linked Immunosorbent AssayHemagglutination Inhibition TestsHumansImmunoglobulin Class SwitchingImmunoglobulin GImmunoglobulin MInfluenza A Virus, H9N2 SubtypeInfluenza, HumanMiceMice, KnockoutReceptors, Antigen, T-Cell, gamma-deltaAntibodies, ViralCytokinesImmunoglobulin GImmunoglobulin MReceptors, Antigen, T-Cell, gamma-deltaantigen-specific antibodyimmunoglobulin class switchingplasma cellT follicular helper cellVγ9Vδ2-T cell

Identifiers

PMID29670614
PMCPMC5893649
OpenAlexW2795923836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.