Evidence map›Paper›PMID 29670523›Full record

ArticleFrontiers in pharmacology2018

Qianlie Xiaozheng Decoction Induces Autophagy in Human Prostate Cancer Cells via Inhibition of the Akt/mTOR Pathway.

Yuehua Xu, Xueting Cai, Bin Zong, Rui Feng, Yali Ji, Gang Chen, Zhongxing Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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  9. The nucleolus, an ally, and an enemy of cancer cells.Histochemistry and cell biology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yuehua XuZhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, China.
Xueting CaiAffiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Bin ZongZhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, China.
Rui FengZhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, China.
Yali JiZhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, China.
Gang ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhongxing LiZhenjiang Hospital of Chinese Traditional and Western Medicine, Zhenjiang, China.
Jiangsu Provincial Academy of Traditional Chinese Medicine · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Qianlie Xiaozheng decoction (QLXZD), a traditional Chinese medicinal formula, has been used clinically to treat advanced prostate cancer (PCa) for more than 10 years. However, experimental evidence supporting its efficacy is lacking. Here, we investigated the anticancer properties and molecular mechanism of QLXZD

Indexed as

Akt/mTOR pathwayautophagyPC3 cellprostate cancerQianlie Xiaozheng decoction

Identifiers

PMID29670523
PMCPMC5893804
OpenAlexW2796329059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.