ArticleClinical and experimental gastroenterology2018
Systemic inflammatory response syndrome and model for end-stage liver disease score accurately predict the in-hospital mortality of black African patients with decompensated cirrhosis at initial hospitalization: a retrospective cohort study.
Article in Clinical and experimental gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Association of Cystatin C Level with All-cause Mortality in Patients with Liver Cirrhosis: A Meta-analysis.Current medicinal chemistry · 2024Pooled it
- Correlation between systemic inflammatory response syndrome and prognosis of patients with cirrhosis and hepatic encephalopathy.BMC gastroenterology · 2025Article
- Prognostic value of neutrophil count to albumin ratio in patients with decompensated cirrhosis.Scientific reports · 2023Observational
- HDL-C levels added to the MELD score improves 30-day mortality prediction in Asian patients with cirrhosis.The Journal of international medical research · 2022Observational
- Systemic Inflammatory Response Syndrome in Patients Hospitalized for Acute Decompensation of Cirrhosis.Canadian journal of gastroenterology & hepatology · 2021Article
- Organ System Network Disruption Is Associated With Poor Prognosis in Patients With Chronic Liver Failure.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSystemic inflammatory response syndrome (SIRS) and model for end-stage liver disease (MELD) predict short-term mortality in patients with cirrhosis. Prediction of mortality at initial hospitalization is unknown in black African patients with decompensated cirrhosis.
aimThis study aimed to look at the role of MELD score and SIRS as the predictors of morbidity and mortality at initial hospitalization. PATIENTS AND
methodsIn this retrospective cohort study, we enrolled 159 patients with cirrhosis (median age: 49 years, 70.4% males). The role of Child-Pugh-Turcotte (CPT) score, MELD score, and SIRS on mortality was determined by the Kaplan-Meier method, and the prognosis factors were assessed with Cox regression model.
resultsAt initial hospitalization, 74.2%, 20.1%, and 37.7% of the patients with cirrhosis showed the presence of ascites, hepatorenal syndrome, and esophageal varices, respectively. During the in-hospital follow-up, 40 (25.2%) patients died. The overall incidence of mortality was found to be 3.1 [95% confidence interval (CI): 2.2-4.1] per 100 person-days. Survival probabilities were found to be high in case of patients who were SIRS negative (log-rank test= 4.51,
conclusionMELD score and SIRS can be used as tools for the prediction of mortality in black African patients with decompensated cirrhosis.
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