Evidence map›Paper›PMID 29670385›Full record

ArticleClinical, cosmetic and investigational dermatology2018

The efficacy of a pseudo-ceramide and eucalyptus extract containing lotion on dry scalp skin.

Yutaka Takagi, Xuanhe Ning, Akihiko Takahashi, Chiaki Ishizaki, Takahiro Nishizaka, Kazuhiro Kaizu, Masahiro Miyaki, Hotaka Yamamuro, Makoto Kawashima

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Efficacy of hydrophilic or lipophilic emulsions containingClinical, cosmetic and investigational dermatology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yutaka TakagiSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Xuanhe NingSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Akihiko TakahashiSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Chiaki IshizakiEbisu Skin Research Center, Inforward, Inc., Tokyo, Japan.
Takahiro NishizakaSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Kazuhiro KaizuSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Masahiro MiyakiSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Hotaka YamamuroSkin Care Product Research, Kao Corporation, Tokyo, Japan.
Makoto KawashimaDepartment of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.
Kao Corporation (Japan) · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDry and scaly conditions on the scalp are often observed in patients with atopic dermatitis, seborrheic dermatitis and/or pityriasis capitis. Those scalp lesions often exhibit low barrier function and reduced ceramide levels. Therefore, a clinical study was conducted to evaluate the efficacy of topical application of a pseudo-ceramide and eucalyptus extract-containing lotion on the scalps of patients with skin diseases.

methodsThirty-four subjects participated in this study (atopic dermatitis: 19 subjects; seborrheic dermatitis: 6 subjects; pityriasis capitis: 9 subjects). After 4 weeks of daily treatment with a pseudo-ceramide and eucalyptus extract-containing lotion, the skin symptoms had significantly improved in all patients with those skin diseases.

resultsSkin dryness, scaling, and erythema were significantly improved by treatment with the lotion. The moisture-retention ability of the scalp was significantly increased and itchiness, evaluated using a visual analog scale, decreased significantly. Accompanying those improvements was a significant improvement in the quality of life of the subjects, evaluated by the Skindex-16

conclusionFrom these results, we conclude that this pseudo-ceramide and eucalyptus extract-containing lotion effectively improved the dry and scaly conditions of the scalp as well as the quality of life of subjects with atopic dermatitis, seborrheic dermatitis, or pityriasis capitis.

Indexed as

formulationinflammationmoisturizationscalp lotionsensitive skinskin care

Identifiers

PMID29670385
PMCPMC5896640
OpenAlexW2795367575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.