ArticleInternational journal of chronic obstructive pulmonary disease
Prediction of severe exacerbations and mortality in COPD: the role of exacerbation history and inspiratory capacity/total lung capacity ratio.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Long-term cost and utility consequences of short-term clinically important deterioration in patients with chronic obstructive pulmonary disease: results from the TORCH study.International journal of chronic obstructive pulmonary disease · 2019Trial
- Article
- Treatment With Bilevel PAP Is Associated With a Reduction in Severe Exacerbations in COPD-OSA Overlap: A Retrospective Claims Analysis.CHEST pulmonary · 2025Article
- Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline.International journal of chronic obstructive pulmonary disease · 2025Article
- Association between the Static and Dynamic Lung Function and CT-Derived Thoracic Skeletal Muscle Measurements-A Retrospective Analysis of a 12-Month Observational Follow-Up Pilot Study.Advances in respiratory medicine · 2024Observational
- MULTI-VIEW CNN FOR TOTAL LUNG VOLUME INFERENCE ON CARDIAC COMPUTED TOMOGRAPHY.Proceedings. IEEE International Symposium on Biomedical Imaging · 2023Article
- Cost-Effectiveness of Humidified High-Flow Therapy (HHFT) for COPD Patients on Long-Term Oxygen Therapy.ClinicoEconomics and outcomes research : CEOR · 2023Article
- Analyses of Factors Associated with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Review.International journal of chronic obstructive pulmonary disease · 2023Review
- D-dimer/Fibrinogen ratio and recurrent exacerbations might have a potential impact to predict 90-day mortality in patients with COPD exacerbation.Malawi medical journal : the journal of Medical Association of Malawi · 2021Article
- Future concepts in bronchodilation for COPD: dual-European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Predictors of delayed extubation following lung resection: Focusing on preoperative pulmonary function and incentive spirometry.Journal of the Chinese Medical Association : JCMA · 2021Article
- Article
- COPD Exacerbation History and Impact on Future Exacerbations - 8-Year Retrospective Observational Database Cohort Study from Germany.International journal of chronic obstructive pulmonary disease · 2021Observational
- Incidence and predictors of COPD mortality in Uganda: A 2-year prospective cohort study.PloS one · 2021Article
- Article
- Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts.The Lancet. Respiratory medicine · 2020Article
- Article
- Understanding exacerbation risk in BLVR: A logistic regression approach to complication prediction.Chronic respiratory diseaseArticle
- Comparison of health-related quality of life measures in asthma-COPD overlap.Chronic respiratory diseaseArticle
- Treatable Traits in COPD - A Proposed Approach.International journal of chronic obstructive pulmonary diseaseReview
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere exacerbations and mortality are major outcomes in COPD, and risk factors for these events are actively searched for. Several predictors of mortality have been identified in COPD. The inspiratory capacity/total lung capacity (IC/TLC) ratio has been shown to be a strong predictor of all cause and respiratory mortality in patients with COPD. The major objectives of this study were to analyze which clinical parameters, including lung volumes, were the best predictors of the 5-year cumulative risk of hospital admissions or death and the 5-year risk of exacerbations, in stable COPD patients.
methodsThis study retrospectively reviewed data from 98 stable COPD patients, consecutively recruited in 2012. Forced expiratory volume in 1 s (FEV
resultsThe cumulative 5-year combined risk of hospital admission or death was significantly predicted by the ExH and the IC/TLC ratio. Analyzing separately group D, FEV
conclusionExH and IC/TLC ratio were the best predictors of the most severe outcomes in COPD (admissions or mortality), independently of COPD severity. FEV
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