ArticleJournal of exposure science & environmental epidemiology2018
Blood total mercury and methylmercury among pregnant mothers in Charleston, South Carolina, USA.
Article in Journal of exposure science & environmental epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Effects of low doses of methylmercury (MeHg) exposure on definitive endoderm cell differentiation in human embryonic stem cells.Archives of toxicology · 2023Article
- Total Blood Mercury Predicts Methylmercury Exposure in Fish and Shellfish Consumers.Biological trace element research · 2022Article
- Transport and Toxicity of Methylmercury-Cysteine in Cultured BeWo Cells.International journal of molecular sciences · 2021Article
- Connecting inorganic mercury and lead measurements in blood to dietary sources of exposure that may impact child development.World journal of methodology · 2021Review
- Total blood mercury and its determinants in New Zealand children and adults.Journal of exposure science & environmental epidemiology · 2021Article
- Exposure to total and methylmercury among pregnant women in Suriname: sources and public health implications.Journal of exposure science & environmental epidemiology · 2021Article
- Leaf ethanolic extract ofToxicological research · 2020Article
- Longitudinal changes during pregnancy in gut microbiota and methylmercury biomarkers, and reversal of microbe-exposure correlations.Environmental research · 2019Article
- Chemical analysis of Hg0-containing Hindu religious objects.PloS one · 2019Article
- NRXN1 Deletion and Exposure to Methylmercury Increase Astrocyte Differentiation by Different Notch-Dependent Transcriptional Mechanisms.Frontiers in genetics · 2019Article
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4 authors.
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Abstract
backgroundMaternal blood total mercury (THg) is a biomarker for prenatal methylmercury (MeHg) exposure. Few studies have quantified both blood THg and MeHg during pregnancy, and few studies have reported longitudinal trends.
objectivesWe analyzed blood THg and MeHg in a cohort of pregnant mothers in Charleston, South Carolina (n = 83), and investigated whether blood THg or MeHg changed between early and late gestation.
methodsTHg and MeHg were analyzed in blood samples from early (12 ± 1.7 weeks) and late (35 ± 2.2 weeks) gestation.
resultsBlood %MeHg (of THg) averaged 63% (range: 10-114%) and 61% (range: 12-117%) during early and late gestation, respectively. In unadjusted analyses, blood MeHg decreased from early to late pregnancy (paired t-test, p = 0.04), while THg did not change (paired t-test, p = 0.34). When blood MeHg was normalized by the hematocrit, this decrease was no longer statistically significant (paired t-test, p = 0.09).
conclusionsIn unadjusted analyses, blood MeHg, but not THg, decreased significantly between early and late gestation; this decrease was due in part to hemodilution. Percent MeHg (of THg) varied by up to one order of magnitude. Results highlight the importance of Hg speciation in maternal blood samples to assess prenatal MeHg exposure.
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