Evidence map›Paper›PMID 29669873›Full record

ReviewStroke2018

Exosome Therapy for Stroke.

Jieli Chen, Michael Chopp

Abstract readReview
In one paragraph

Review in Stroke, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Temperature-modulated separation of therapeutic cells, viral vectors, and exosomes using functional polymers.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. LncRNAs Orchestrating Neuroinflammation: A Comprehensive Review.Cellular and molecular neurobiology · 2025
    Review
  18. Review
  19. Review
  20. Review

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jieli ChenFrom the Department of Neurology, Henry Ford Hospital, Detroit, MI (J.C., M.C.) mchopp1@hfhs.org jieli@neuro.hfh.edu.
Michael ChoppFrom the Department of Neurology, Henry Ford Hospital, Detroit, MI (J.C., M.C.) mchopp1@hfhs.org jieli@neuro.hfh.edu.

Funding

Investigation of D-4F effects of neurovascular remodeling after diabetic strokeR01NS097747 · NINDS · HENRY FORD HEALTH SYSTEM · PI CUI, XU, JIANG, QUAN · 2017 to 2021
$2.2M
Neurorestorative therapy of stroke with HUCBC in type two diabetic miceR01NS083078 · NINDS · HENRY FORD HEALTH SYSTEM · PI CHEN, JIELI · 2014 to 2018
$1.6M
miR-17-92 exosome treatment of strokeR01NS088656 · NINDS · HENRY FORD HEALTH SYSTEM · PI CHOPP, MICHAEL · 2015 to 2019
$1.6M
MiR-126/ABCA1 mediates exosome induced neurorestorative effects after stroke in T2DM miceR01NS099030 · NINDS · HENRY FORD HEALTH SYSTEM · PI CHEN, JIELI · 2016 to 2018
$984k
NINDS NIH HHS R01 NS083078NINDS NIH HHS R01 NS088656NINDS NIH HHS R01 NS097747NINDS NIH HHS R01 NS099030
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adipose TissueBlood-Brain BarrierBlood PlateletsCell-Derived MicroparticlesExosomesHumansMesenchymal Stem CellsMicroRNAsOrganelle BiogenesisStem CellsStrokeThrombosisMicroRNAsexosomeslipidsmesenchymal stromal cellsmicroRNAsstroke

Identifiers

PMID29669873
PMCPMC6028936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.