Evidence map›Paper›PMID 29669809›Full record

ArticleThe Journal of biological chemistry2018

Two distinct sites of client protein interaction with the chaperone cpSRP43.

Camille Z McAvoy, Alex Siegel, Samantha Piszkiewicz, Emily Miaou, Mansen Yu, Thang Nguyen, Annie Moradian, Michael J Sweredoski, Sonja Hess, Shu-Ou Shan

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 4 countries.

Camille Z McAvoyFrom the Division of Chemistry and Chemical Engineering.
Alex SiegelFrom the Division of Chemistry and Chemical Engineering.
Samantha PiszkiewiczFrom the Division of Chemistry and Chemical Engineering.
Emily MiaouFrom the Division of Chemistry and Chemical Engineering.
Mansen YuFrom the Division of Chemistry and Chemical Engineering.
Thang NguyenFrom the Division of Chemistry and Chemical Engineering.
Annie MoradianThe Proteome Exploration Laboratory, and.
Michael J SweredoskiThe Proteome Exploration Laboratory, and.
Sonja HessThe Proteome Exploration Laboratory, and.
Shu-Ou ShanFrom the Division of Chemistry and Chemical Engineering, sshan@caltech.edu.ORCID 0000-0002-6526-1733
California Institute of Technology · US

Funding

PREDOCTORAL TRAINING IN BIOLOGY AND CHEMISTRYT32GM007616 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI STERNBERG, PAUL WARREN · 1985 to 2019
$22.9M
Understanding Molecular Chaperones during Membrane Protein BiogenesisR01GM114390 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI SHAN, SHU-OU · 2016 to 2019
$1.4M
NIGMS NIH HHS R01 GM114390NIGMS NIH HHS T32 GM007616
6 · The paper itself

Abstract

Integral membrane proteins are prone to aggregation and misfolding in aqueous environments and therefore require binding by molecular chaperones during their biogenesis. Chloroplast signal recognition particle 43 (cpSRP43) is an ATP-independent chaperone required for the biogenesis of the most abundant class of membrane proteins, the light-harvesting chlorophyll

Indexed as

Protein Interaction MapsArabidopsisArabidopsis ProteinsChlorophyll Binding ProteinsModels, MolecularPhotosystem II Protein ComplexPoint MutationProtein AggregatesProtein ConformationProtein Interaction Domains and MotifsSignal Recognition ParticleArabidopsis ProteinsChlorophyll Binding ProteinscpSRP43 protein, ArabidopsisLHCB5 protein, ArabidopsisPhotosystem II Protein ComplexProtein AggregatesSignal Recognition Particlechaperonechloroplastmembrane proteinprotein targetingsignal recognition particle (SRP)

Identifiers

PMID29669809
PMCPMC5995501
OpenAlexW2801261699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.