Evidence map›Paper›PMID 29669806›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus.

Ioannis Gavvovidis, Matthias Leisegang, Gerald Willimsky, Natalie Miller, Paul Nghiem, Thomas Blankenstein

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Targeting Cancer with CRISPR/Cas9-Based Therapy.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Review
  14. Current concepts and approaches to merkel cell carcinoma.Archives of dermatological research · 2021
    Review
  15. Review
  16. Selective reactivation of STING signaling to target Merkel cell carcinoma.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ioannis GavvovidisMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
Matthias LeisegangInstitute of Immunology, Charité, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Gerald WillimskyInstitute of Immunology, Charité, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Natalie MillerUniversity of Washington, Dermatology/Medicine/Pathology, Seattle, Washington.
Paul NghiemUniversity of Washington, Dermatology/Medicine/Pathology, Seattle, Washington.
Thomas BlankensteinMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany. tblanke@mdc-berlin.de.
German Cancer Research Center · DE

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Pathogenetic and prognostic studies for improved therapy of Merkel cell carcinomaK24CA139052 · NCI · UNIVERSITY OF WASHINGTON · PI NGHIEM, PAUL · 2009 to 2018
$1.8M
Humoral and cellular immunity in polyomavirus-linked Merkel cell carcinomaR01CA162522 · NCI · UNIVERSITY OF WASHINGTON · PI NGHIEM, PAUL · 2011 to 2015
$1.6M
NCI NIH HHS K24 CA139052NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA162522
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic TherapyAnimalsAntigens, Viral, TumorCarcinogenesisCarcinoma, Merkel CellCytotoxicity, ImmunologicEpitopesGene Expression Regulation, NeoplasticHLA-A2 AntigenHumansImmunotherapyLymphocytesMerkel cell polyomavirusMiceMice, TransgenicOncogene Proteins, ViralAntigens, Viral, TumorEpitopesHLA-A2 AntigenOncogene Proteins, ViralPDCD1 protein, humanProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-Cell

Identifiers

PMID29669806
PMCPMC6082703
OpenAlexW2803087123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.