Evidence map›Paper›PMID 29669754›Full record

ArticleBlood advances2018

Ectopic Lck expression in CLL demarcates intratumoral subpopulations with aberrant B-cell receptor signaling.

Efthymia Theofani, Spyridon Alexis, Paul Costeas, Christos Andriopoulos, Georgia Feleskoura, Panagiotis Zikos, Anthi Aktypi, Alexandros Spyridonidis, Konstantina Nika

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. A Novel Peptide that Disrupts the Lck-IPArchives of microbiology & immunology · 2023
    Article
  3. Article
  4. Beyond TCR Signaling: Emerging Functions of Lck in Cancer and Immunotherapy.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Efthymia TheofaniDepartment of Biochemistry, School of Medicine, University of Patras, Patras, Greece.
Spyridon AlexisBone Marrow Transplantation Unit and FACS Laboratory, University Hospital of Patras, Patras, Greece.
Paul CosteasThe Center for the Study of Haematological Malignancies, Nicosia, Cyprus.
Christos AndriopoulosBone Marrow Transplantation Unit and FACS Laboratory, University Hospital of Patras, Patras, Greece.
Georgia FeleskouraBone Marrow Transplantation Unit and FACS Laboratory, University Hospital of Patras, Patras, Greece.
Panagiotis ZikosGeneral Hospital of Patras "Agios Andreas," Patras, Greece; and.
Anthi AktypiSpecialist Physician Haematologist, Patras, Greece.
Alexandros SpyridonidisBone Marrow Transplantation Unit and FACS Laboratory, University Hospital of Patras, Patras, Greece.
Konstantina NikaDepartment of Biochemistry, School of Medicine, University of Patras, Patras, Greece.
General University Hospital of Patras · GRUniversity of Patras · GRAgios Andreas Hospital · GRCenter for the Study of Childhood and Adolescence · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic HeterogeneityCD5 AntigensHumansLeukemia, Lymphocytic, Chronic, B-CellLymphocyte Specific Protein Tyrosine Kinase p56(lck)Receptors, Antigen, B-CellSignal TransductionCD5 AntigensLymphocyte Specific Protein Tyrosine Kinase p56(lck)Receptors, Antigen, B-Cell

Identifiers

PMID29669754
PMCPMC5916004
OpenAlexW2801724998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.