Evidence map›Paper›PMID 29669714›Full record

ArticleMolecular pharmacology2018

Cannabidiol Inhibits Endocannabinoid Signaling in Autaptic Hippocampal Neurons.

Alex Straiker, Michaela Dvorakova, Anaelle Zimmowitch, Ken Mackie

Open access · bronzeAbstract read
In one paragraph

Article in Molecular pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Acute effects of ΔPsychopharmacology · 2022
    Trial
  4. A randomised controlled trial of vaporised ΔEuropean archives of psychiatry and clinical neuroscience · 2019
    Trial
  5. Review
  6. Review
  7. Article
  8. Phytocannabinoids restore seizure-induced alterations in emotional behaviour in male rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  9. Review
  10. Review
  11. Cannabinoid inhibition of mechanosensitive KbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alex StraikerGill Center for Biomolecular Science, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana straiker@indiana.edu.
Michaela DvorakovaGill Center for Biomolecular Science, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Anaelle ZimmowitchGill Center for Biomolecular Science, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Ken MackieGill Center for Biomolecular Science, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.
Indiana University Bloomington · US

Funding

Project 3 - In vivo pharmacology of cannabinoid receptor probesP01DA009158 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI Alexandros Makriyannis · 1994 to 2026
$26.0M
A Novel Pharmacotherapy for GlaucomaR01EY024717 · NEI · NORTHEASTERN UNIVERSITY · PI THAKUR, GANESH A · 2014 to 2018
$2.2M
Cannabinoid Modulation of Cell FunctionK05DA021696 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI MACKIE, KENNETH · 2007 to 2017
$1.3M
Harnessing endogenous cannabinoids for ocular healthR01EY024625 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI STRAIKER, ALEXANDER J · 2014 to 2017
$1.3M
NEI NIH HHS R01 EY024625NEI NIH HHS R01 EY024717NIDA NIH HHS K05 DA021696NIDA NIH HHS P01 DA009158
6 · The paper itself

Abstract

Δ

Indexed as

AnimalsCannabidiolCannabinoidsEndocannabinoidsHippocampusMiceNeuronal PlasticityNeuronsReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Signal TransductionCannabidiolCannabinoidsEndocannabinoidsReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2

Identifiers

PMID29669714
PMCPMC5988021
OpenAlexW2802417482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.