Evidence map›Paper›PMID 29669690›Full record

ArticleThe Science of the total environment2018

Spatial clustering of metal and metalloid mixtures in unregulated water sources on the Navajo Nation - Arizona, New Mexico, and Utah, USA.

Joseph H Hoover, Eric Coker, Yolanda Barney, Chris Shuey, Johnnye Lewis

Abstract read
In one paragraph

Article in The Science of the total environment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Uranium Isotopes: From Geosciences to Biomedical Sciences.Current environmental health reports · 2026
    Review
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Drinking water and health assessment in a Northern Arizona community.Human and ecological risk assessment : HERA · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph H HooverCommunity Environmental Health Program, College Of Pharmacy, University of New Mexico, 1 University of New Mexico, Albuquerque, NM 87131, USA. Electronic address: johoover@salud.unm.edu.
Eric CokerCenter for Environmental Research and Children's Health, School of Public Health, University of California Berkeley, USA.
Yolanda BarneyNavajo Nation Environmental Protection Agency - Public Water Systems Supervisory Program, PO Box 339, Window Rock, AZ 86515, USA.
Chris ShueySouthwest Research and Information Center, 105 Stanford Drive SE, Albuquerque, NM 87106, USA.
Johnnye LewisCommunity Environmental Health Program, College Of Pharmacy, University of New Mexico, 1 University of New Mexico, Albuquerque, NM 87131, USA.

Funding

FAIR Data Competency and Machine Learning Readiness for Biomedical ScientistsK12GM088021 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI REBECCA S. HARTLEY, Diane Lidke · 2009 to 2026
$16.4M
UNM Metals Exposure and Toxicity Assessment on tribal Lands in the Southwest (METALS) Superfund Research ProgramP42ES025589 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CERRATO, JOSE MANUEL · 2017 to 2025
$16.4M
Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
New Mexico NIEHS CenterP30ES012072 · NIEHS · UNIVERSITY OF NEW MEXICO · PI BURCHIEL, SCOTT WILLIAM · 2003 to 2007
$4.1M
Project 2: Development of biomarkers of autoimmunity in 3 tribal communities exposed to mixed metal contaminantsP50ES026102 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI GONZALES, MELISSA · 2015 to 2019
$3.6M
Navajo Uranium Assessment and Kidney Health ProjectR01ES014565 · NIEHS · UNIVERSITY OF NEW MEXICO · PI LEWIS, JOHNNYE L · 2006 to 2010
$2.4M
Dine'Network For Environmental Health (DiNEH) ProjectR25ES013208 · NIEHS · UNIVERSITY OF NEW MEXICO · PI LEWIS, JOHNNYE L · 2004 to 2007
$898k
FIC NIH HHS D43 TW010540NIEHS NIH HHS P30 ES012072NIEHS NIH HHS P42 ES025589NIEHS NIH HHS P50 ES026102NIEHS NIH HHS R01 ES014565NIEHS NIH HHS R25 ES013208NIGMS NIH HHS K12 GM088021
6 · The paper itself

Abstract

Contaminant mixtures are identified regularly in public and private drinking water supplies throughout the United States; however, the complex and often correlated nature of mixtures makes identification of relevant combinations challenging. This study employed a Bayesian clustering method to identify subgroups of water sources with similar metal and metalloid profiles. Additionally, a spatial scan statistic assessed spatial clustering of these subgroups and a human health metric was applied to investigate potential for human toxicity. These methods were applied to a dataset comprised of metal and metalloid measurements from unregulated water sources located on the Navajo Nation, in the southwest United States. Results indicated distinct subgroups of water sources with similar contaminant profiles and that some of these subgroups were spatially clustered. Several profiles had metal and metalloid concentrations that may have potential for human toxicity including arsenic, uranium, lead, manganese, and selenium. This approach may be useful for identifying mixtures in water sources, spatially evaluating the clusters, and help inform toxicological research investigating mixtures.

Indexed as

Metal and metalloid mixturesSpatial clusteringUnregulated water sources

Identifiers

PMID29669690
PMCPMC6051417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.