ArticleBMC biology2018
Genomics analysis of Aphanomyces spp. identifies a new class of oomycete effector associated with host adaptation.
Article in BMC biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Eukaryotic metagenome-assembled genomes recovered from deep metagenomic sequencing of the seagrass,Microbial genomics · 2026Article
- Comparative Genomics Provide Insight Into the Evolution of European Aphanomyces euteiches Strains.Genome biology and evolution · 2026Article
- Article
- Transcriptomic analysis identifies candidate genes for Aphanomyces root rot disease resistance in pea.BMC plant biology · 2024Article
- Genome analysis ofFrontiers in microbiology · 2023Article
- Phyto-oxylipin mediated plant immune response to colonization and infection in the soybean-Frontiers in plant science · 2023Article
- The root pathogenFrontiers in plant science · 2023Article
- A Comprehensive Assessment of the Secretome Responsible for Host Adaptation of the Legume Root PathogenJournal of fungi (Basel, Switzerland) · 2022Article
- Comparative Genomic Analyses Provide Insight Into the Pathogenicity ofFrontiers in microbiology · 2022Article
- Lytic Polysaccharide Monooxygenases as Chitin-Specific Virulence Factors in Crayfish Plague.Biomolecules · 2021Article
- Genome Analysis ofPlants (Basel, Switzerland) · 2021Article
- Predicting Lifestyle from Positive Selection Data and Genome Properties in Oomycetes.Pathogens (Basel, Switzerland) · 2021Article
- Mining oomycete proteomes for metalloproteases leads to identification of candidate virulence factors in Phytophthora infestans.Molecular plant pathology · 2021Article
- A Meta-Analysis to Determine the State of Biological Control of Aphanomyces Root Rot.Frontiers in molecular biosciences · 2021Review
- Diverse Trajectories Drive the Expression of a Giant Virus in the Oomycete Plant PathogenFrontiers in microbiology · 2021Article
- From effectors to effectomes: Are functional studies of individual effectors enough to decipher plant pathogen infectious strategies?PLoS pathogens · 2020Review
- Comparative analyses of saprotrophy in Salisapilia sapeloensis and diverse plant pathogenic oomycetes reveal lifestyle-specific gene expression.FEMS microbiology ecology · 2020Article
- Comparative Genomics Analyses of Lifestyle Transitions at the Origin of an Invasive Fungal Pathogen in the GenusmSphere · 2020Article
- Long-Read Genome Sequence of the Sugar Beet Rhizosphere MycoparasiteG3 (Bethesda, Md.) · 2020Article
- Characterization of Two Satellite DNA Families in the Genome of the Oomycete Plant PathogenFrontiers in genetics · 2020Article
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOomycetes are a group of filamentous eukaryotic microorganisms that have colonized all terrestrial and oceanic ecosystems, and they include prominent plant pathogens. The Aphanomyces genus is unique in its ability to infect both plant and animal species, and as such exemplifies oomycete versatility in adapting to different hosts and environments. Dissecting the underpinnings of oomycete diversity provides insights into their specificity and pathogenic mechanisms.
resultsBy carrying out genomic analyses of the plant pathogen A. euteiches and the crustacean pathogen A. astaci, we show that host specialization is correlated with specialized secretomes that are adapted to the deconstruction of the plant cell wall in A. euteiches and protein degradation in A. astaci. The A. euteiches genome is characterized by a large repertoire of small secreted protein (SSP)-encoding genes that are highly induced during plant infection, and are not detected in other oomycetes. Functional analysis revealed an SSP from A. euteiches containing a predicted nuclear-localization signal which shuttles to the plant nucleus and increases plant susceptibility to infection.
conclusionCollectively, our results show that Aphanomyces host adaptation is associated with evolution of specialized secretomes and identify SSPs as a new class of putative oomycete effectors.
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